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ProteomicsDistinct Combinatorial Cascade of Events Generated by ECM Proteolysis Dictates Cell Behavior, part 2
It is well established that the expression profiles of multiple and possibly redundant matrix remodeling proteases (e.g. collagenases) strongly differentiates in disease and development. Although enzymatic redundancy might be inferred from their close similarity in structure, their in-vivo activity ...
ORGANISM(S): Rattus norvegicus (Rat) 
2016-09-27 | PXD003796 | Pride
Proteomics Ecm 
ProteomicsDysregulated Proteolysis of Extracellular Matrix Proteins Regulates Influenza and Pneumonia Co-infection Associated Mortality
The balance between tissue integrity and efficient immune response is critical for host survival. Here we investigate the role of extra cellular matrix (ECM)-remodeling events in the lung during influenza infection. Using an unbiased genomic and proteomic approach we follow the dynamics of gene and ...
ORGANISM(S): Mus musculus (Mouse) 
2019-11-19 | PXD004871 | Pride
Influenza Pneumonia Extracellular matrix proteins 
ProteomicsDistinct Combinatorial Cascade of Events Generated by ECM Proteolysis Dictates Cell Behavior
It is well established that the expression profiles of multiple and possibly redundant matrix remodeling proteases (e.g. collagenases) strongly differentiates in disease and development. Although enzymatic redundancy might be inferred from their close similarity in structure, their in-vivo activity ...
ORGANISM(S): Rattus norvegicus (Rat) 
2016-09-27 | PXD003553 | Pride
Proteomics Metalloproteinase Ecm 
UnknownADAM17 selectively activates the IL-6 trans-signaling/ERK MAPK axis in KRAS-addicted lung cancer
Not available
S-SCDT-EMM-2018-09976 | biostudies-other
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