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MetabolomicsGut microbiota-derived butyric acid protected against secondary brain injury after SAH by inhibiting neuronal pyroptosis and regulating gut microbiota composition (Human assays)

BACKGROUND: Subarachnoid hemorrhage (SAH) is a devastating cerebrovascular disease with a poor prognosis. Accumulating studies have reported that gut microbiota contributes to the pathophysiology of several central nervous system diseases. However, whether SAH can change gut micr...

2024-07-09 | MTBLS9087 | MetaboLights
MetabolomicsGut microbiota-derived butyric acid protected against secondary brain injury after SAH by inhibiting neuronal pyroptosis and regulating gut microbiota composition (Murine assays)

BACKGROUND: Subarachnoid hemorrhage (SAH) is a devastating cerebrovascular disease with a poor prognosis. Accumulating studies have reported that gut microbiota contributes to the pathophysiology of several central nervous system diseases. However, whether SAH can change gut micr...

2024-07-09 | MTBLS9100 | MetaboLights
TranscriptomicsTargeted disruption of the BCL9/beta-catenin complex in cancer
Stabilized Alpha-Helix peptides of BCL9 HD2 (SAH-BCL9) block BCL9 and B9L interactions with beta-catenin and specifically downregulate Wnt target gene expression. RNA from triplicate SAH-BCL9B- and vehicle-treated DLD1 samples (10 µM each for 12 hours) was hybridized to Affymetrix Human U133 Plus 2....
ORGANISM(S): Homo sapiens 
2012-08-23 | E-GEOD-33143 | biostudies-arrayexpress
GenomicsBurkholderia orbicola strain:SAH 5-5
Burkholderia orbicola strain:SAH 5-5 Genome sequencing
PRJNA1287893 | ENA
TranscriptomicsTranscription profiling by array of the effect of SAH on brain cells in white matter region of mice
Using the SAH model to conduct experiments, set 5 groups of experimental groups and 5 groups of control groups. Studying the effects on the white matter cells of normal mice and the mice with SAH
ORGANISM(S): Mus musculus 
2019-10-10 | E-MTAB-8407 | biostudies-arrayexpress
TranscriptomicsTranscription profiling of rat cerebral arteries from rats after experimental SAH with the expression in cerebral vessels from sham operated animals
We have compared the gene-expression in cerebral arteries from rats after experimental SAH with the expression in cerebral vessels from sham operated animals. The model is well characterised (Prunell et al. 2003; Prunell et al. 2004) regarding the physiological changes but not regarding the gene exp...
ORGANISM(S): Rattus norvegicus 
2006-01-01 | E-MEXP-338 | biostudies-arrayexpress
GenomicsEscherichia coli strain:sAH/DM23
Escherichia coli strain:sAH/DM23 Genome sequencing
PRJNA1309326 | ENA
GenomicsHalorubrum aethiopicum strain:SAH-A6
Halorubrum aethiopicum strain:SAH-A6 Genome sequencing and assembly
PRJNA302707 | ENA
TranscriptomicsS-adenosylmethionine (SAM) changes DNA methylation patterns in prostate cancer cells
Genome-wide DNA methylation profiling of human PC3 invasive prostate cancer cell line treated with vehicle control (SAH, S-adenosylhomocysteine) and with SAM (S-adenosylmethionine) as well as of untreated human LNCaP non-invasive prostate cancer cell line. The Illumina Infinium 450k Human DNA Methyl...
ORGANISM(S): Homo sapiens 
2015-03-01 | E-GEOD-62053 | biostudies-arrayexpress
GenomicsGene expression data from mouse brain endothelial cells after SAH
Gene expression data from mouse brain endothelial cells after SAH
PRJNA648765 | ENA
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