Sort   by:  
 Page size 
TranscriptomicsU937 scramble vs shHDAC2 upon SAHA (Vorinostat; suberoylanilide hydroxamic acid) treatment
Transcriptional profiling of U937 scramble vs shHDAC2 before and after SAHA treatment at 5µM concentration for 6 and 24 hours. Different Experimental Conditions: U937 scramble (U937 trasfected with empty vector) vs shHDAC2 (U937 trasfected with shHDAC2 vector), untreated and treated with SAHA at 5 ...
ORGANISM(S): Homo sapiens 
2015-02-18 | E-GEOD-37529 | biostudies-arrayexpress
TranscriptomicsGenome-wide analysis of parental and wild-type SK-N-Be(2)C neuroblastoma cell lines as well as those co-treated with the histone deacetylase inhibitor SAHA
Analysis of varied biologic pathways in neuroblastoma SK-N-Be(2)C cells grown in doxorubicin and/or SAHA. We hypothesized that SK-N-Be(2)C cells undergo a mesenchymal change through mesenchymal change resulting in a more invasive as well as drug resistant phenotype, and that the mechanism of SAHAs e...
ORGANISM(S): Homo sapiens 
2016-05-31 | E-GEOD-47669 | biostudies-arrayexpress
TranscriptomicsGenome-wide analysis of parental wild-type and derived doxorubicin resistant SK-N-SH neuroblastoma cell lines as well as those co-treated with the histone deacetylase inhibitor SAHA
Analysis of varied biologic pathways in neuroblastoma SK-N-SH cells grown in doxorubicin and/or SAHA. The hypothesis was that SK-N-SH cells undergo a mesenchymal change through mesenchymal change resulting in a more invasive as well as drug resistant phenotype, and that the mechanism of SAHAs effect...
ORGANISM(S): Homo sapiens 
2016-05-31 | E-GEOD-47668 | biostudies-arrayexpress
GenomicsSAHA-ZIM Data Access Committee
Data Access Committee EGAC00001000509
EGAC00001000509 | EGA
TranscriptomicsDifferential Transcriptomic Modulation by Histone Deacetylase Inhibitor SAHA in LUAD and LUSC
Background: Histone deacetylases (HDACs) drive non-small-cell lung cancer (NSCLC) progression, yet HDAC inhibitor (HDACi) responses vary by tumor subtype. We compared the pan-HDAC inhibitor SAHA (vorinostat) in two NSCLC models-HER2-mutant lung adenocarcinoma (NCI-H1299; TP53del, NRASQ61K) and EGFR/...
ORGANISM(S): Homo sapiens 
2026-02-25 | GSE302469 | GEO
ProteomicsCharacterization of U937 cells after SAHA treatment
U937 cells were treated with SAHA and DMSO. Proteome and phosphoproteome were measured by TMT10 LC-MS.
ORGANISM(S): Homo sapiens (Human) 
2026-04-06 | PXD063064 | Pride
Phosphoproteome Human Proteome 
UnknownProtein folding by domain V of Escherichia coli 23S rRNA: specificity of RNA-protein interactions.
Not available
S-EPMC2347393 | biostudies-literature
UnknownA novel approach to detect resistance mechanisms reveals FGR as a factor mediating HDAC inhibitor SAHA resistance in B-cell lymphoma.
Not available
S-EPMC5423193 | biostudies-literature
TranscriptomicsHistone deacetylase inhibitors antagonize distinct pathways to suppress tumorigenesis of embryonal rhabdomyosarcoma.
Embryonal rhabdomyosarcoma (ERMS) is the most common soft tissue cancer in children and is characterized by myogenic differentiation arrest. The prognosis of patients with relapsed or metastatic disease remains poor. ERMS genomes show few recurrent mutations, suggesting that other molecular mechani...
ORGANISM(S): Homo sapiens 
2015-12-21 | E-GEOD-74970 | biostudies-arrayexpress
UnknownDifferential transcriptomic modulation by histone deacetylase inhibitor SAHA in LUAD and LUSC.
Not available
S-EPMC12918457 | biostudies-literature
Sort   by:  
 Page size