Dataset Information

Characterization of U937 cells after SAHA treatment

ABSTRACT: U937 cells were treated with SAHA and DMSO. Proteome and phosphoproteome were measured by TMT10 LC-MS.

INSTRUMENT(S):

ORGANISM(S): Homo Sapiens (human)

TISSUE(S): Monocyte, Cell Culture

DISEASE(S): Lymphoma

SUBMITTER: Tommaso De Marchi

LAB HEAD: Carmela Dell'Aversana

PROVIDER: PXD063064 | Pride | 2026-04-06

REPOSITORIES: Pride

ACCESS DATA

Dataset's files

Source:

			Action	DRS
	20240115.hs.uni.sprot.CAN.fasta	Fasta
	20250324.Fragpipe.PROTEOME.zip	Other
	20250331.Fragpipe.PHOSPHO.zip	Other
	TDM_M2503_222.raw	Raw
	TDM_M2503_223.raw	Raw

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1 - 5 of 39

Publications

Dynamic epigenetic regulation of BCLAF1 splicing in acute myeloid leukemia.

Sgueglia Giulia G Massaro Crescenzo C Muro Annamaria A Lettiero Ida I D'Agostino Erika E Favale Gregorio G Simonelli Nicla N Del Gaudio Nunzio N Carafa Vincenzo V De Marchi Tommaso T Rotili Dante D Valente Sergio S Mai Antonello A Sbardella Gianluca G De Simone Mariacarla M Altucci Lucia L Dell'Aversana Carmela C

Cell death & disease 20260324 1

Dysregulation of alternative splicing is increasingly associated with cancer development and tumor progression. BCL2-associated transcription factor 1 (BCLAF1) is involved in a wide range of biological processes and it is continuously being investigated due to its intricate function in tumorigenesis and drug resistance. In acute myeloid leukemia (AML) cell lines, we identified two distinct, unbalanced isoforms of BCLAF1: the full-length isoform, which exhibits oncogenic properties, and the short ...[more]

PMID: 41872140

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