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TranscriptomicsRNA-seq of chemically reset human naive pluripotent stem cells
A simple method is presented to reset human pluripotent cells to a naive state via transient histone deacetylase inhibition and maintenance in chemically-defined naive stem cell culture media. Cells can be reset without transgenes and expanded continuously either on feeders or alternative substrates...
ORGANISM(S): Homo sapiens 
2017-08-07 | E-MTAB-5674 | biostudies-arrayexpress
GenomicsA high-throughput screen of inactive X chromosome reactivation identifies the enhancement of DNA demethylation by 5-aza-2’-dC upon inhibition of ribonucleotide reductase-wide
Background: DNA methylation is important for maintenance of the silent state of genes on the inactive X chromosome (Xi). Here, we screened for siRNAs and chemicals that reactivate an Xi-linked reporter in the presence of 5-aza-2’-deoxycytidine (5-aza-2’-dC), an inhibitor of DNA methyltransferase 1, ...
ORGANISM(S): Homo sapiens 
2015-08-25 | E-GEOD-72295 | biostudies-arrayexpress
UnknownEfficacy and Safety of Respiratory Syncytial Virus (RSV) Prefusion F Protein Vaccine (RSVPreF3 OA) in Older Adults Over 2 RSV Seasons.
Not available
S-EPMC11175669 | biostudies-literature
UnknownDelivery of acute ischaemic stroke treatments in the European region in 2019 and 2020.
Not available
S-EPMC10472963 | biostudies-literature
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