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TranscriptomicsGene expression changes induced by MV130 (Bactek®) in human monocytes-derived dendritic cells.
MV130 is a commercially polyvalent bacterial preparation, which has shown to reduce the the rate of respiratory infections in patients suffering from recurrent respiratory tract infections. However, the immunological mechanisms associated to this clinical benefit remain unknown. We wanted to identif...
ORGANISM(S): Homo sapiens 
2017-12-14 | E-MTAB-5259 | biostudies-arrayexpress
Transcriptomicsp27 binds to promoters of multiple genes leading to their repression
The role of the cyclin-cdk inhibitor p27 in tumorigenesis is still a controversial matter. We demonstrate here that p27 negatively regulates transcription of a number of genes (p27-target genes) involved in key cellular functions as RNA processing, translation, respiration and cell proliferation. Cr...
ORGANISM(S): Mus musculus 
2011-12-01 | E-GEOD-20068 | biostudies-arrayexpress
TranscriptomicsExpression data from p27delta51 MEFs cells in quiescence
Low levels of the cell cycle regulator p27Kip1 are associated with a worse outcome in many tumor types. We report here a new regulatory role of p27Kip1 as a transcriptional regulator. In association with transcriptional repressors such as p130, E2F4 and HDACs, p27 binds to promoters of multiple gene...
ORGANISM(S): Mus musculus 
2011-12-01 | E-GEOD-20064 | biostudies-arrayexpress
TranscriptomicsExpression data from p27WT, p27CK and KO MEFs cells in quiescence
Low levels of the cell cycle regulator p27Kip1 are associated with a worse outcome in many tumor types. We report here a new regulatory role of p27Kip1 as a transcriptional regulator. In association with transcriptional factors such as ETS and E2F4 and co-repressors like p130, HDACs and mSin3A, p27 ...
ORGANISM(S): Mus musculus 
2011-12-01 | E-GEOD-27672 | biostudies-arrayexpress
UnknownIn-hospital care, complications, and 4-month mortality following a hip or proximal femur fracture: the Spanish registry of osteoporotic femur fractures prospective cohort study.
Not available
S-EPMC6153683 | biostudies-literature
UnknownMortality after surgery in Europe: a 7 day cohort study.
Not available
S-EPMC3493988 | biostudies-literature
UnknownElective surgery cancellations due to the COVID-19 pandemic: global predictive modelling to inform surgical recovery plans.
Not available
S-EPMC7272903 | biostudies-literature
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