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Background: Histone deacetylase (HDAC) is strongly associated with epigenetic regulation and carcinogenesis, and its inhibitors induce the differentiation or apoptosis of cancer cells. Valproic acid (VPA) is one of the clinically available HDAC inhibitors. We investigated the anticancer effects of V...
ORGANISM(S): Homo sapiens 
We successfully constructed a customized spectral library containing information on 1,394 proteins for DIA-MS; the library can be used for comprehensive identification and quantification of proteins expressed in the mouse bones.
ORGANISM(S): Mus Musculus (mouse) 
This project is “Medical proteome analysis of osteoporosis- and bone mass-related proteins using the Kibo Japanese Experiment Module of International Space Station (ISS)”. Utilizing proteomic technologies, this research aims to identify proteins involved in space flight-induced osteopenia as well as...
ORGANISM(S): Mus Musculus (mouse) 
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