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TranscriptomicsResponse of tobacco cells to Glucan elicitor
We have previously reported that the responses of tobacco tissues treated with AaGlucan are similar to those for laminarin [1]. To better understand the overall responses and signaling pathways in tobacco, we have identified here AaGlucan and laminarin early response genes, using a custom 16K BY-2 m...
ORGANISM(S): Nicotiana tabacum 
2007-10-16 | E-GEOD-6948 | biostudies-arrayexpress
MetabolomicsMetabolomic Characterization of Knock-Out Mutants in Arabidopsis - Development of a Metabolite Profiling Database for Knock-Out Mutants in Arabidopsis (MeKO)
Despite recent intensive research efforts in functional genomics, the functions of only a limited number of Arabidopsis (Arabidopsis thaliana) genes have been determined experimentally. Thus, improving gene annotation remains a major challenge in plant science. Because metabolite profiling can chara...
2014-03-01 | MTBLS47 | MetaboLights
TranscriptomicsExamination of the function of NtMYBGR1 and NtDC1B in tobacco BY-2 cells.
Overexpression lines for each of NtMYBGR1 (Genbank accession No. AB279612) and NtDC1B (Genbank accession No. AB279614) were used to characterize the function of NtMYBGR1 and NtDC1B in tobacco BY-2 cells. We then analyzed the effect of overexpression of these genes on the expression of other genes, ...
ORGANISM(S): Nicotiana tabacum 
2007-10-15 | E-GEOD-6949 | biostudies-arrayexpress
TranscriptomicsRNA-seq of human monocytic cell line (THP-1) treated with compound #42 (2D216), LPS, #42(2D216)/LPS, or vehicle controls
To explore the effects of compound #42 on RNA transcription of THP-1 cells, we performed RNA-seq analysis.
ORGANISM(S): Homo sapiens 
2022-01-12 | E-MTAB-10222 | biostudies-arrayexpress
TranscriptomicsMicroarray analysis of gene expression under different light conditions
The size of tomato fruits are largely dependent on growth conditions. To obtain insights on how light intensity contributes to translocation from a leaf and a fruit, we developed a plant irradiation system based on light-emitting diodes (LEDs) to a leaf. By using this system, we investigated the cha...
ORGANISM(S): Solanum lycopersicum 
2012-05-01 | E-GEOD-35020 | biostudies-arrayexpress
MetabolomicsEnhancement of oxidative and drought tolerance in Arabidopsis by overaccumulation of antioxidant flavonoids
The notion that plants use specialized metabolism to protect against environmental stresses needs to be experimentally proven by addressing the question of whether stress tolerance by specialized metabolism is directly due to metabolites such as flavonoids. We report that flavonoids with radical sca...
2013-12-06 | MTBLS57 | MetaboLights
TranscriptomicsRNA-seq of human monocytic cell line (THP-1) treated with compound 81 or vehicle controls
To explore the effects of compound 81 on RNA transcription of THP-1 cells, we performed RNA-seq analysis.
ORGANISM(S): Homo sapiens 
2021-12-14 | E-MTAB-10269 | biostudies-arrayexpress
ProteomicsUse of data-independent acquisition mass spectrometry to identify an objective serum indicator of the need for osteoporotic therapeutic intervention
Osteoporosis is characterized by weakened bone microstructure and loss of bone mass. Current diagnostic criteria for osteoporosis are based on the T-score, which is a measure of bone mineral density. However, osteoporotic fragility fractures can occur regardless of the T-score, underscoring the need...
ORGANISM(S): Homo Sapiens (human) 
2024-04-10 | PXD041546 | JPOST Repository
ProteomicsComprehensive human serum spectral library
For a comprehensive analysis of the human serum proteome, we constructed a spectral library for DIA-MS. Our spectral library contained information on 20,303 peptides derived from 1,597 human serum proteins. We believe that the constructed spectral library will be useful for proteomic analysis of hum...
ORGANISM(S): Homo Sapiens (human) 
2024-04-10 | PXD041558 | JPOST Repository
ProteomicsChanges in the astronaut serum proteome during prolonged spaceflight
The molecular mechanisms associated with spaceflight-induced biological adaptations that may affect many healthy tissue functions remain poorly understood. In this study, we analyzed temporal changes in the serum proteome of six astronauts during prolonged spaceflight missions using quantitative com...
ORGANISM(S): Homo Sapiens (human) 
2024-01-22 | PXD044609 | JPOST Repository
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