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TranscriptomicsTracing the conversion process for primordial germ cells to pluripotent stem cells
The overall gene expression profiles revealed by this system provide novel insight into how pluripotency is acquired in germ-committed cells. In the study presented here, we employed FACS sorting to purify pluripotent candidate cells during the culture period
ORGANISM(S): Mus musculus 
2012-04-24 | E-GEOD-37261 | biostudies-arrayexpress
TranscriptomicsDifferentially expressed genes among motor and prefrontal areas of macaque monkey neocortex
Motor-related areas of neocortex are highly differentiated into several subareas from both functional and cytoarchitectural aspects in the higher primates. To assess the molecular basis of such areal specialization, we investigated the gene expression profiles of primary motor area (M1), premotor ar...
ORGANISM(S): Macaca mulatta 
2007-08-31 | E-GEOD-8644 | biostudies-arrayexpress
TranscriptomicsComparision of expression profile between wild-type and Slc39a13 knockout osteoblasts
In order to explore molecules whose expression is controlled by Slc39a13, we investigated gene expression profiling of primary osteoblast isolated from wild-type and Slc39a13 knockout mice. Keywords: knockout vs wild-type wild-type vs Slc39a13 knockout
ORGANISM(S): Mus musculus 
2008-11-07 | E-GEOD-10555 | biostudies-arrayexpress
ProteomicsRapid and Label-Free Structural Proteomics by One-Step Swift Trypsin LiP-MS
We developed a rapid, surface-targeted limited proteolysis workflow, Swift Trypsin LiP-MS (STLiP-MS), to profile proteome-wide structural changes under near-native conditions. STLiP-MS uses a trypsin-immobilized spin column and centrifugation-controlled contact to achieve instantaneous, highly repro...
ORGANISM(S): Homo Sapiens (human) Cellular Organisms 
2026-01-05 | PXD069771 | JPOST Repository
TranscriptomicsInduced pluripotent stem cells from CINCA syndrome patients as a model for dissecting somatic mosaicism and drug discovery
Chronic infantile neurological cutaneous and articular (CINCA) syndrome is an IL-1-driven autoinflammatory disorder caused mainly by NLRP3 mutations. The pathogenesis of CINCA syndrome patients who carry NLRP3 mutations as somatic mosaicism has not been precisely described because of the difficulty ...
ORGANISM(S): Homo sapiens 
2012-06-10 | E-GEOD-38626 | biostudies-arrayexpress
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