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TranscriptomicsCardiac phase-targeted dynamic load on left ventricle differentially regulates phase-sensitive gene expressions and pathway activation
Each heart was assigned to one of the following three conditions: phasic systolic overload (SO), phasic diastolic overload (DO), and no loading throughout the cardiac cycle (control; CN). We created SO by isovolumic contraction (peak systolic LVP > 170 mmHg) at a constant diastolic volume with end-d...
ORGANISM(S): Rattus norvegicus 
2013-02-07 | E-GEOD-44108 | biostudies-arrayexpress
TranscriptomicsA novel combination of serum microRNAs for detecting breast cancer in the early stage
MicroRNAs (miRNAs), which are stably present in serum, have been reported to be potentially useful for detecting cancer. In the present study, we examined the expression profiles of serum miRNAs in large cohorts to identify the miRNAs that can be used to detect breast cancer in the early stage. We c...
ORGANISM(S): Homo sapiens 
2016-01-21 | E-GEOD-73002 | biostudies-arrayexpress
TranscriptomicsTranscriptional profiling of the T. thermophilus HB8 response to hydrogen peroxide
We observed the expression profile of the total mRNA in Thermus thermophilus HB8 wild-type strain at 0, 5, 15 and 30 min after the addition of 10 mM H2O2. Three wild-type strain of T. thermophilus HB8 were pre-cultured at 70 degC for 16 hours in 2 mL of TT medium containing 0.8% polypeptone, 0.4% ye...
ORGANISM(S): Thermus thermophilus HB8 
2010-10-15 | E-GEOD-21430 | biostudies-arrayexpress
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