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ProteomicsAging induces hepatic oxidative stress and nuclear proteomic remodelling in liver from Wistar ratAging induces hepatic oxidative stress and nuclear proteomic remodelling in liver from Wistar rats
Aging induces oxidative stress and proteome remodeling in the nucleus from liver in Wistar rats
ORGANISM(S): Rattus norvegicus (Rat) 
2022-02-17 | PXD027773 | Pride
Oxidative stress nuclear liver wistar rat lc-ms/ms 
UnknownExploring Propolis as a Sustainable Bio-Preservative Agent to Control Foodborne Pathogens in Vacuum-Packed Cooked Ham.
The search for natural food additives makes propolis an exciting alternative due to its known antimicrobial activity. This work aims to investigate propolis' behavior as a nitrite substitute ingredient in cooked ham (a ready-to-eat product) when confronted with pathogenic microorganisms of food inte...
S-EPMC11124515 | biostudies-literature
UnknownEffects of an Optimized Aged Garlic Extract on Cardiovascular Disease Risk Factors in Moderate Hypercholesterolemic Subjects: A Randomized, Crossover, Double-Blind, Sustainedand Controlled Study.
The consumption of aged black garlic (ABG) has been related to improvements in several cardiovascular disease (CVD) risk factors. However, the extent of the beneficial effects depends on the garlic aging process and the amount and type of chemical compounds accumulated. The main objective of this st...
S-EPMC8838962 | biostudies-literature
UnknownThe role of gender in a smoking cessation intervention: a cluster randomized clinical trial.

Background

The prevalence of smoking in Spain is high in both men and women. The aim of our study was to evaluate the role of gender in the effectiveness of a specific smoking cessation intervention conducted in Spain.

Methods

This study was a secondary analysis of a cluster randomize...
S-EPMC3125366 | biostudies-literature
UnknownExtracellular vesicles from Listeria monocytogenes-infected dendritic cells alert the innate immune response.
Communication through cell-cell contacts and extracellular vesicles (EVs) enables immune cells to coordinate their responses against diverse types of pathogens. The function exerted by EVs in this context depends on the proteins and nucleic acids loaded into EVs, which elicit specific responses invo...
S-EPMC9483171 | biostudies-literature
UnknownClinical impact of chronic obstructive pulmonary disease on non-cystic fibrosis bronchiectasis. A study on 1,790 patients from the Spanish Bronchiectasis Historical Registry.

Background

Few studies have evaluated the coexistence of bronchiectasis (BE) and chronic obstructive pulmonary disease (COPD) in series of patients diagnosed primarily with BE. The aim of this study was to analyse the characteristics of patients with BE associated with COPD included in the S...
S-EPMC5436841 | biostudies-literature
UnknownN-antigenemia detection by a rapid lateral flow test predicts 90-day mortality in COVID-19: A prospective cohort study.

Objectives

To evaluate if the detection of N antigen of SARS-CoV-2 in plasma by a rapid lateral flow test predicts 90-day mortality in COVID-19 patients hospitalized at the wards.

Methods

The presence of N-antigenemia was evaluated in the first 36 hours after hospitalization in 600 un...
S-EPMC9150910 | biostudies-literature
UnknownEffect of viral storm in patients admitted to intensive care units with severe COVID-19 in Spain: a multicentre, prospective, cohort study.

Background

The contribution of the virus to the pathogenesis of severe COVID-19 is still unclear. We aimed to evaluate associations between viral RNA load in plasma and host response, complications, and deaths in critically ill patients with COVID-19.

Methods

We did a prospective coho...
S-EPMC10129133 | biostudies-literature
UnknownPriming of dendritic cells by DNA-containing extracellular vesicles from activated T cells through antigen-driven contacts.
Interaction of T cell with antigen-bearing dendritic cells (DC) results in T cell activation, but whether this interaction has physiological consequences on DC function is largely unexplored. Here we show that when antigen-bearing DCs contact T cells, DCs initiate anti-pathogenic programs. Signals o...
S-EPMC6037695 | biostudies-literature
UnknownRelevance of DNA repair gene polymorphisms to gastric cancer risk and phenotype.
Variations in DNA repair genes have been reported as key factors in gastric cancer (GC) susceptibility but results among studies are inconsistent. We aimed to assess the relevance of DNA repair gene polymorphisms and environmental factors to GC risk and phenotype in a Caucasian population in Spain. ...
S-EPMC5482622 | biostudies-literature
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