Sort   by:  
 Page size 
UnknownAmbra1 haploinsufficiency in CD1 mice results in metabolic alterations and exacerbates age-associated retinal degeneration.
Macroautophagy/autophagy is a key process in the maintenance of cellular homeostasis. The age-dependent decline in retinal autophagy has been associated with photoreceptor degeneration. Retinal dysfunction can also result from damage to the retinal pigment epithelium (RPE), as the RPE-retina constit...
S-EPMC9980615 | biostudies-literature
UnknownTrimethylamine N-oxide is a new plant molecule that promotes abiotic stress tolerance.
Trimethylamine N-oxide (TMAO) is a well-known naturally occurring osmolyte in animals that counteracts the effect of different denaturants related to environmental stress and has recently been associated with severe human chronic diseases. In plants, however, the presence of TMAO has not yet been re...
S-EPMC8133759 | biostudies-literature
UnknownThe actin module of endocytic internalization in Aspergillus nidulans: A critical role of the WISH/DIP/SPIN90 family protein Dip1.
Using fluorescent protein-tagged F-actin reporters we studied the actin cytoskeleton in Aspergillus nidulans. F-actin probes labeled endocytic patches, contractile actin rings and the Spitzenkörper (SPK), but not exocytic cables generated by the SPK-associated formin, illuminated only by tropomyosin...
S-EPMC12422587 | biostudies-literature
UnknownDissecting the Polyhydroxyalkanoate-Binding Domain of the PhaF Phasin: Rational Design of a Minimized Affinity Tag.
Phasin PhaF from Pseudomonas putida consists of a modular protein whose N-terminal domain (BioF) has been demonstrated to be responsible for binding to the polyhydroxyalkanoate (PHA) granule. BioF has been exploited for biotechnological purposes as an affinity tag in the functionalization of ...
S-EPMC7267194 | biostudies-literature
UnknownAerobic-anaerobic transition boosts poly(3-hydroxybutyrate-co-3-hydroxyvalerate) synthesis in Rhodospirillum rubrum: the key role of carbon dioxide.

Background

Microbially produced bioplastics are specially promising materials since they can be naturally synthesized and degraded, making its end-of-life management more amenable to the environment. A prominent example of these new materials are polyhydroxyalkanoates. These polyesters serve...
S-EPMC9999600 | biostudies-literature
UnknownExploring Rhodospirillum rubrum response to high doses of carbon monoxide under light and dark conditions.
Environmental concerns about residues and the traditional disposal methods are driving the search for more environmentally conscious processes, such as pyrolysis and gasification. Their main final product is synthesis gas (syngas) composed of CO, CO2, H2, and methane. Syngas ca...
S-EPMC10927898 | biostudies-literature
UnknownExceptional Evolution of a Squamous Odontogenic Tumor in the Jaw: Molecular Approach.
A squamous odontogenic tumor (SOT) is an epithelial locally benign neoplasia derived from the periodontium of the jaws. It is considered a lesion of low incidence. Predominantly, it affects the mandible, although both jaw bones may be involved. Here, we discuss the malignant clinical evolution of an...
S-EPMC11395408 | biostudies-literature
UnknownType III intermediate filaments as targets and effectors of electrophiles and oxidants.
Intermediate filaments (IFs) play key roles in cell mechanics, signaling and homeostasis. Their assembly and dynamics are finely regulated by posttranslational modifications. The type III IFs, vimentin, desmin, peripherin and glial fibrillary acidic protein (GFAP), are targets for diverse modificati...
S-EPMC7381704 | biostudies-literature
UnknownRevealing the essential role of the lid in mclPHA intracellular depolymerase from Pseudomonas putida KT2440.
Polyhydroxyalkanoates (PHAs) are microbial polyesters that serve as intracellular carbon reserves and represent promising biodegradable alternatives to conventional plastics. However, their large-scale application requires not only cost-effective production but also efficient strategies for recovery...
S-EPMC12504323 | biostudies-literature
UnknownAssembly of bacterial cell division protein FtsZ into dynamic biomolecular condensates.
Biomolecular condensation through phase separation may be a novel mechanism to regulate bacterial processes, including cell division. Previous work revealed that FtsZ, a protein essential for cytokinesis in most bacteria, forms biomolecular condensates with SlmA, a protein that protects the chromoso...
S-EPMC8529516 | biostudies-literature
Sort   by:  
 Page size