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ProteomicsSoluble TREM2 inhibits secondary nucleation of Aβ fibrillization and enhances cellular uptake of fibrillar Aβ
We used sTREM2 obtained from bacterial expression system to form a complex with Aβ40 fibrils in vitro. This complex was chemically cross-linked using two cross-linkers, BS3 and NHSF.
ORGANISM(S): Escherichia Coli 
2022-01-05 | PXD030722 |
ProteomicsConformational dynamics of the activated GLP-1 receptor-Gs complex revealed by cross-linking mass spectrometry and integrative modeling
Despite revolutionary advancements in GPCR structural biology, our understanding of the complexity of GPCR activation and signaling would not be complete without complementary information on the conformational dynamics. Yet it is particularly challenging to study the dynamics of GPCR complexes with ...
ORGANISM(S): Homo Sapiens 
2023-01-08 | PXD039315 |
TranscriptomicsTranscription profiling of human 27 non-labored normal preterm and 9 non-labored normal term basal plate samples to investigate gene expression at the human maternal-fetal interface
Microarray analysis to globally assess gene expression at the maternal-fetal interface Experiment Overall Design: 27 non-labored normal preterm and 9 non-labored normal term basal plate samples were analyzed on Affymetrix U133 chips using established protocols. The gene expression profile of prete...
ORGANISM(S): Homo sapiens 
2008-11-07 | E-GEOD-5999 | biostudies-arrayexpress
ProteomicsMolecular Architecture of the Yeast Mediator Complex
Cross-linking MS data from the yeast Mediator complex. Cross-linking was performed using either BS3 or 1:1 mix of d0:d12 DSS. Includes unfractionated, SEC enriched, high pH reverse phase fractionated, DDA and inclusion list generated files.
ORGANISM(S): Saccharomyces Cerevisiae (ncbitaxon:4932) 
2015-08-13 | MSV000079237 | MassIVE
UnknownIntegrative structure and functional anatomy of a nuclear pore complex
Not available
EMPIAR-10162 | biostudies-other
UnknownStructure–function mapping of a heptameric module in the nuclear pore complex
Not available
S-JCBD-201109008 | bioimages
ProteomicsA SARS-CoV-2-Human Protein-Protein Interaction Map Reveals Drug Targets and Potential Drug-Purposing
An outbreak of the novel coronavirus SARS-CoV-2, the causative agent of COVID-19 respiratory disease, has infected over 170,000 people since the end of 2019, killed over 7,400, and caused worldwide social and economic disruption. SARS-CoV-2 infection has a mortality rate of 3.4% among confirmed case...
ORGANISM(S): Severe Acute Respiratory Syndrome Coronavirus 2 (ncbitaxon:2697049) Homo Sapiens (ncbitaxon:9606) 
2020-03-24 | MSV000085144 | MassIVE
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