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MetabolomicsComplete pathway elucidation and heterologous reconstitution of Rhodiola salidroside biosynthesis
Salidroside is a bioactive tyrosine-derived phenolic natural product found in medicinal plants under the Rhodiola genus. In addition to their roles in traditional medicine as anti-fatigue and anti-anoxia adaptogens, Rhodiola total extract and salidroside have also displayed medicinal properties as a...
2018-01-25 | MTBLS566 | MetaboLights
TranscriptomicsEffects of Salidroside on gene expression in ischemic brain of rats
We employed DNA microarray to identify genes differentially regulated by salidroside in ischemic brain of MCAO rats. With a cut of p < .01 and 2-fold change, we found that 121 genes were upregulated and 142 genes were down-regulated in the MCAO group, compared to the sham group. Administration of sa...
ORGANISM(S): Rattus norvegicus 
2015-10-30 | E-GEOD-52001 | biostudies-arrayexpress
TranscriptomicsEffects of Salidroside on gene expression in ischemic brain of rats
We employed DNA microarray to identify genes differentially regulated by salidroside in ischemic brain of MCAO rats. With a cut of p < .01 and 2-fold change, we found that 121 genes were upregulated and 142 genes were down-regulated in the MCAO group, compared to the sham group. Administration of sa...
ORGANISM(S): Rattus norvegicus 
2015-10-30 | GSE52001 | GEO
Transcriptomics15-Lipoxygenase-2 Deficiency Induces a Dysfunction in Macrophages that can be Restored by Salidroside
15-Lipoxygenase-2 (15-LOX-2) is thought to regulate inflammation and immunological function; however, its mechanisms of action are still unclear. Furthermore, it has been reported that salidroside has anti-inflammatory properties, but its role in macrophage function is not yet understood. In this st...
ORGANISM(S): Mus musculus 
2021-10-04 | GSE184840 | GEO
UnknownThe metabolism of salidroside to its aglycone p-tyrosol in rats following the administration of salidroside.
Not available
S-EPMC4125138 | biostudies-literature
Genomics15-Lipoxygenase-2 Deficiency Induces a Dysfunction in Macrophages that can be Restored by Salidroside
15-Lipoxygenase-2 Deficiency Induces a Dysfunction in Macrophages that can be Restored by Salidroside
PRJNA766638 | ENA
UnknownSalidroside Inhibits Myogenesis by Modulating p-Smad3-Induced Myf5 Transcription.
Not available
S-EPMC5858519 | biostudies-literature
UnknownMechanism of salidroside against coronary artery disease by network pharmacology analysis.
Not available
S-EPMC10258957 | biostudies-literature
UnknownProduction of salidroside in metabolically engineered Escherichia coli.
Not available
S-EPMC4200411 | biostudies-literature
UnknownSalidroside as a Novel Protective Agent to Improve Red Blood Cell Cryopreservation.
Not available
S-EPMC5025239 | biostudies-literature
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