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MetabolomicsThe omics data were used to reveal the role of aaNAT1 in the salivary glands of Aedes aegypti and the changes in metabolites in the salivary glands of Aedes aegypti after blood-feeding.

The salivary glands of Aedes aegypti were collected separately from the following four groups: those injected with AaaaNAT1 dsRNA, those injected with GUS dsRNA, those after blood-feeding, and those without any treatment. Metabolomic analysis was performed on these four sample groups to...

2025-11-17 | MTBLS13324 | MetaboLights
MetabolomicsEffect of short-term use of FFP2 (N95) masks on the salivary metabolome of young healthy volunteers: a pilot study.
The use of face masks has become an integral part of public life in the post-pandemic era. However, the understanding of the effect of wearing masks on physiology remains incomplete and is required for informing public health policies. For the first time, we report the effects of wearing FFP2 masks ...
2024-08-07 | MTBLS5803 | MetaboLights
MetabolomicsSynergistic metabolism of salivary MUC5B in oral commensal bacteria during early biofilm formation

Bacterial metabolism in oral biofilms is comprised of complex networks of nutritional chains and biochemical regulations. These processes involve both intraspecies and interspecies networks as well as interactions with components from host saliva, gingival crevicular fluid, and dietary intake. In...

2023-10-30 | MTBLS8370 | MetaboLights
MetabolomicsSalivary MUC5B Modulation of Glucose Metabolism in Early Oral Biofilms
To investigate how early mono- and dual species biofilms of oral Actinomyces naeslundii and Streptococcus gordonii clinical isolates metabolized glucose in the presence of the complex salivary mucin MUC5B, this study employed NMR-based metabolomics with interpretation of network integration. Untarge...
2024-09-11 | MTBLS10078 | MetaboLights
MetabolomicsExploring Salivary Metabolites as Biomarkers in Chronic Craniofacial and Orofacial Pain: A Metabolomic Analysis.
Chronic facial pain (CFP) includes a range of conditions such as musculoskeletal, neurovascular, and neuropathic disorders affecting the facial and jaw regions, often causing significant distress to patients. This study aims to investigate the metabolomic profile of patients with CFP, focusing on sa...
2025-07-16 | MTBLS12704 | MetaboLights
MetabolomicsIdentification of Salivary Lipid Biomarkers for Noninvasive Diagnosis of Reflux Esophagitis via UHPLC-MS-based Lipidomics
Introduction Reflux esophagitis (RE) is a common upper gastrointestinal disorder, and its diagnosis currently relies primarily on invasive endoscopic examination. The lack of reliable non-invasive biomarkers substantially limits early detection and large-scale screening. Saliva represents a promisin...
2026-03-31 | MTBLS14198 | MetaboLights
TranscriptomicsTranscriptomic and functional analysis of the Anopheles gambiae salivary gland in relation to blood feeding
Background: The Anopheles gambiae salivary glands play a major role in malaria transmission and express a variety of bioactive components that facilitate blood-feeding by preventing platelet aggregation, blood clotting, vasodilatation, and inflammatory and other reactions at the probing site on the ...
ORGANISM(S): Anopheles gambiae 
2011-11-01 | E-GEOD-33385 | biostudies-arrayexpress
MetabolomicsSalivary Multi-omics Characterization and Staging Diagnostic Model for Type 2 Diabetes with Different Stages of Periodontitis

Background: This study aims to comprehensively characterize the dynamic succession of the salivary microbiome and metabolic reprogramming in type 2 diabetes mellitus (T2DM) patients across progressive stages of periodontitis (Stage I–IV) using an integrated multi-omics approach. We specifica...

2026-05-20 | MTBLS13827 | MetaboLights
TranscriptomicsAtlas of Gene Expression at Microanatomical Resolution of the Submandibular Salivary Gland
The goal of this study was to generate a spatiotemporal atlas of gene expression in the developing salivary gland. This will allow us to identify changes in gene expression that may result in the formation of the different domains of the salivary gland. At least 4 microarrays per location per time ...
ORGANISM(S): Mus musculus 
2011-07-01 | E-GEOD-22828 | biostudies-arrayexpress
TranscriptomicsTranscriptomic analysis of Anopheles stephensi salivary glands during Plasmodium berghei infection
RNA-seq of Anopheles stephensi salivary glands during Plasmodium berghei infection
ORGANISM(S): Anopheles stephensi 
2015-11-05 | E-MTAB-3964 | biostudies-arrayexpress
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