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ProteomicsProteomic characterization of native and decellularized rat submandibular gland scaffolds prepared using the S3T1 protocol
Salivary gland hypofunction lacks effective regenerative treatment, and organ-specific decellularized extracellular matrix scaffolds represent a promising biomaterial platform for tissue engineering. In this study, rat submandibular glands were decellularized using a rapid S3T1 workflow consisting o...
ORGANISM(S): Rattus norvegicus (Rat) 
2026-04-21 | PXD077315 | Pride
Extracellular matrix scaffold Proteomics Dia Rat Submandibular gland Salivary gland tissue engineering Decellularization Lc-ms/ms 
UnknownDevelopment of poly(ethylene glycol) hydrogels for salivary gland tissue engineering applications.
Not available
S-EPMC4449707 | biostudies-literature
TranscriptomicsTranscription profiling by array of parotid tissue from Primary Sjögren’s Syndrome and controls
Primary Sjögren’s syndrome (pSS) is a chronic autoimmune disease with complex etiopathogenesis. Here we use Affymetrix U133 plus 2.0 microarray gene expression data from human parotid tissue. Parotid gland tissues were harvested from 17 pSS and 14 14 non-pSS sicca patients and 18 controls. The data ...
ORGANISM(S): Homo sapiens 
2012-09-06 | E-GEOD-40611 | biostudies-arrayexpress
TranscriptomicsSalivary gland during development and onset of xerostomia in murine model of SjM-CM-6gren's syndrome-like disease
Differential gene expression in the salivary gland during development and onset of xerostomia in SjM-CM-6grenM-bM-^@M-^Ys syndrome-like disease of the C57BL/6.NOD-Aec1Aec2 mouse. Recently, we reported the development of the C57BL/6.NOD-Aec1Aec2 mouse that carries two genetic intervals derived from t...
ORGANISM(S): Mus musculus 
2009-04-11 | E-GEOD-15640 | biostudies-arrayexpress
TranscriptomicsGene expression profile of the Myd88 gene depletion on mouse salivary glands
MyD88 is an important adaptor protein for signal transduction downstream of Toll-like receptors and TACI, receptors for regulation of innate immunity and B cell responses, respectively. The surfaces of oral mucosa are protected from infections by antimicrobial proteins and natural immunoglobulins th...
ORGANISM(S): Mus musculus 
2014-09-19 | E-GEOD-61339 | biostudies-arrayexpress
TranscriptomicsExpression data on salivary glands tissues of 3rd instar larvae from w[1118] wildtype and dTCTP mutants.
Drosophila translationally controled tumor protein (dTCTP) is important to repair double stranded DNA breaks in cell nucleus. However, besides damaged DNA loci, dTCTP is also located in interbands region of polytene chromsomes of salivary gland tissues. To address whether dTCTP is involved in transc...
ORGANISM(S): Drosophila melanogaster 
2016-08-16 | E-GEOD-75900 | biostudies-arrayexpress
Transcriptomics18h before puparium formation vs. puparium formation tissue comparisons
Samples at 18h before puparium formation were compared to samples at puparium formation for each the following tissues: epidermis with attached muscle, salivary gland, wing disc, midgut, and central nervous system. Keywords = Drosophila, ecdysone, network, genomic, microarray, organogenesis, EcR, mi...
ORGANISM(S): Drosophila melanogaster 
2010-06-05 | E-GEOD-542 | biostudies-arrayexpress
UnknownBiocompatible tissue scaffold compliance promotes salivary gland morphogenesis and differentiation.
Not available
S-EPMC4029047 | biostudies-literature
TranscriptomicsTranscription profiling of minor salivary glands to identify distinct patterns of gene expression in patients with primary Sj¸gren?s syndrome (pSS), a frequent and prototype systemic autoimmune disease
Analysis of targets organs might help to get new insights into the pathogenesis of autoimmune diseases. We used global gene expression profiling of minor salivary glands to identify distinct patterns of gene expression in patients with primary Sjögren’s syndrome (pSS), a frequent and prototype syste...
ORGANISM(S): Homo sapiens 
2005-10-01 | E-MEXP-419 | biostudies-arrayexpress
TranscriptomicsHeterogeneous genetic profiles in soft tissue myoepitheliomas
Myoepithelioma, mixed tumor and parachordoma are rare soft tissue tumors thought to represent different morphologic variants of the same family of tumors, hereafter referred to as MMP tumors. The genetic basis of these neoplasms is poorly investigated. However, they morphologically resemble mixed tu...
ORGANISM(S): Homo sapiens 
2010-05-25 | E-GEOD-10266 | biostudies-arrayexpress
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