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MetabolomicsSynergistic metabolism of salivary MUC5B in oral commensal bacteria during early biofilm formation

Bacterial metabolism in oral biofilms is comprised of complex networks of nutritional chains and biochemical regulations. These processes involve both intraspecies and interspecies networks as well as interactions with components from host saliva, gingival crevicular fluid, and dietary intake. In...

2023-10-30 | MTBLS8370 | MetaboLights
MetabolomicsSalivary MUC5B Modulation of Glucose Metabolism in Early Oral Biofilms
To investigate how early mono- and dual species biofilms of oral Actinomyces naeslundii and Streptococcus gordonii clinical isolates metabolized glucose in the presence of the complex salivary mucin MUC5B, this study employed NMR-based metabolomics with interpretation of network integration. Untarge...
2024-09-11 | MTBLS10078 | MetaboLights
MetabolomicsIdentification of Salivary Lipid Biomarkers for Noninvasive Diagnosis of Reflux Esophagitis via UHPLC-MS-based Lipidomics
Introduction Reflux esophagitis (RE) is a common upper gastrointestinal disorder, and its diagnosis currently relies primarily on invasive endoscopic examination. The lack of reliable non-invasive biomarkers substantially limits early detection and large-scale screening. Saliva represents a promisin...
2026-03-31 | MTBLS14198 | MetaboLights
MetabolomicsSalivary Multi-omics Characterization and Staging Diagnostic Model for Type 2 Diabetes with Different Stages of Periodontitis

Background: This study aims to comprehensively characterize the dynamic succession of the salivary microbiome and metabolic reprogramming in type 2 diabetes mellitus (T2DM) patients across progressive stages of periodontitis (Stage I–IV) using an integrated multi-omics approach. We specifica...

2026-05-20 | MTBLS13827 | MetaboLights
ProteomicsCross-sectional association of salivary proteins with age, sex, body mass index, smoking, and education
In a cross-sectional approach, we analyzed the influence of age, sex, body mass index (BMI), smoking, and education on salivary protein signatures in whole saliva samples of 187 individuals. Subjects were randomly selected from the population-based Study of Health in Pomerania (SHIP-Trend).
ORGANISM(S): Homo Sapiens (ncbitaxon:9606) 
2019-03-13 | MSV000083569 | MassIVE
TranscriptomicsHigh throughput sequencing of B.henselae infected and non-infected I. ricinus salivary glands
In order to select genes that are differentially expressed in salivary glands during Ixodes ricinus infection by Bartonella henselae we compare the transcriptome of infected and non-infected salivary glands I. ricinus from a pathogen free colony were infected -or not- with B. henselae at the larval ...
ORGANISM(S): Ixodes ricinus 
2015-04-02 | E-GEOD-56746 | biostudies-arrayexpress
ProteomicsHaemaphysalis longicornis salivary gland LC-MSMS
Ticks are notorious carriers of pathogens; these blood-sucking arthropods can spread a variety of deadly diseases. The salivary gland is the main organ in ticks, and this organ begins to develop rapidly when Ixodidae ticks suck blood. When these ticks reach a critical weight, the salivary glands sto...
ORGANISM(S): Haemaphysalis longicornis 
2020-05-26 | PXD013678 | Pride
Salivary gland Haemaphysalis longicornis Lc-msms 
ProteomicsPotato Aphid Salivary Proteome: Identification of Aphid Phosphoproteins and Tomato Host Proteins
Aphids deliver saliva into plants and acquire plant sap for their nourishment using a specialized mouthpart or stylets. Aphid saliva is of great importance as it contains effectors that are involved in modulating host defense and metabolism. Although profiling aphid salivary glands and identifying s...
ORGANISM(S): Macrosiphum Euphorbiae (ncbitaxon:13131) 
2014-12-15 | MSV000078978 | MassIVE
ProteomicsLC-MS/MS of Pseudoregma bambucicola salivary gland and saliva
In this study, liquid chromatography-tandem spectrometry (LC–MS/MS) analysis was conducted to characterize the overall salivary protein composition from dissected salivary glands and secreted saliva in P. bambucicola, and to identify putative effector proteins important for aphid-plant interactions....
ORGANISM(S): Pseudoregma bambucicola 
2023-01-05 | PXD038131 | Pride
Pseudoregma bambucicola、 salivary gland、saliva、proteome 
TranscriptomicsDifferential gene expression profiling in the presence and absence of cohesin in Drosophila salivary glands (gene expression data)
Analysis of differential gene expression in third instar Drosophila salivary glands in the absence versus presence of cohesin. ABSTRACT: Developmental abnormalities observed in Cornelia de Lange Syndrome (CdLS) have been genetically linked to mutations in the cohesin machinery. These findings raise ...
ORGANISM(S): Drosophila melanogaster 
2010-12-22 | E-GEOD-21844 | biostudies-arrayexpress
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