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TranscriptomicsIdentification of a DNA methylation signature in blood from subjects affected by Down syndrome
Down syndrome is characterized by a wide spectrum of clinical signs, which include cognitive and endocrine disorders and haematological abnormalities. Although it is well established that the causative defect of Down syndrome is the trisomy of chromosome 21, the molecular bases of Down syndrome phen...
ORGANISM(S): Homo sapiens 
2015-03-03 | E-GEOD-52588 | biostudies-arrayexpress
TranscriptomicsGene expression analysis of human lymphoblastoid cell lines
Human lymphoblastoid cell lines (EBV-immortalised B cells, LcL) obtained from subjects of different age (young 28-40 years, centenarians >95 years) were analysed for gene expression at basal culture conditions and after 48 hours of serum starvation. Lymphoid B cells from centenarians were more resis...
ORGANISM(S): Homo sapiens 
2011-07-29 | E-GEOD-31040 | biostudies-arrayexpress
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