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ProteomicsMyostatin Deficiency But Not Anti-Myostatin Blockade Induces Marked Proteomic Changes in Mouse Skeletal Muscle
Recent studies have reported the deleterious physiological and metabolic changes in Mstn-/- mice including impaired force generation and susceptibility to contraction-induced injury. Such observations have raised the concerns about the functional quality of the increased muscle resulting from thera...
ORGANISM(S): Mus musculus (Mouse) 
2016-05-31 | PXD003747 | Pride
Myostatin knockout Silac mouse Gastrocnemius Quantitative proteomics Anti-myostatin blocking antibody 
ProteomicsProteogenomic identification of Hepatitis B virus (HBV) genotype-specific HLA-I restricted peptides from HBV-positive patient liver tissues
The presentation of virus-derived peptides by HLA class I molecules on the surface of an infected cell and the recognition of these HLA-peptide complexes by, and subsequent activation of, CD8+ cytotoxic T cells provides an important mechanism for immune protection against viruses. Recent advances in...
ORGANISM(S): Homo sapiens (Human) 
2023-01-03 | PXD037270 | Pride
Proteogenomics Hepatocellular carcinoma Hepatitis b Human leukocyte antigen (hla) Immunopeptidomics 
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