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TranscriptomicsTranscription profiling of Emiliania huxleyi after 6, 12 and 24 hours of viral infection infected with the virus EhV-86 in comparison to an unifected culture
Gene expression analysis of Emiliania huxleyi after 6, 12 and 24 hours of viral infection infected with the virus EhV-86 in comparison to an unifected culture.
ORGANISM(S): Emiliania huxleyi 
2009-12-01 | E-MEXP-2382 | biostudies-arrayexpress
TranscriptomicsGlobal transcriptomic profiling of oxygen-glucose deprivation (OGD)-mediated neuronal injury
Oxygen-glucose deprivation (OGD) is a cellular phenomenon consistently observed upon occurrence of ischemic stroke which eventually results in neuronal death. Neuronal cell death after ischemia takes place via two distinct processes, necrosis and apoptosis. Apoptosis, programmed cell death, is denot...
ORGANISM(S): Mus musculus 
2013-12-31 | E-GEOD-23158 | biostudies-arrayexpress
TranscriptomicsImmune cells direct epithelial maturation during early human lung development
The adult human lung harbours a significant proportion of immune cells, which are known to play a crucial role in both normal lung homeostasis and pathogenesis. In this work, we collected CD45-enriched human lung cells from 6 to 22 week post conception (pcw) and built a single-cell transcriptome and...
ORGANISM(S): Homo sapiens 
2022-12-09 | E-MTAB-11528 | biostudies-arrayexpress
TranscriptomicsTranscriptomics analysis of skeletal muscle in humans with heart failure
Heart failure is a multisystem syndrome caused by structural and functional defects in multiple tissues. The study aims to identify differentially regulated genes in skeletal muscle of heart failure patients. Here, we obtained biopsies from the pectoralis major muscle and performed RNA sequencing to...
ORGANISM(S): Homo sapiens 
2020-09-07 | E-MTAB-8531 | biostudies-arrayexpress
TranscriptomicsGenome-wide comparison of the transcriptomes of highly enriched normal and chronic myeloid leukemia stem and progenitor cell populations
The resistance of CML leukemic stem cells (LSC) to tyrosine kinase inhibitor therapies targeting BCR-ABL leads to persistence of disease in most cases. We have identified novel putative therapeutic targets that are differentially expressed in CML LSCs compared to normal hematopoietic stem cells (HS...
ORGANISM(S): Homo sapiens 
2013-05-08 | E-GEOD-43754 | biostudies-arrayexpress
TranscriptomicsSomatic copy-number mosaicism in human skin revealed by induced pluripotent stem cells (sequencing)
Reprogramming human somatic cells into induced pluripotent stem cells (iPSC) has been suspected of causing de novo copy number variations (CNVs). To explore this issue, we performed a whole-genome and transcriptome analysis of 20 human iPSC lines derived from primary skin fibroblasts of 7 individual...
ORGANISM(S): Homo sapiens 
2012-10-31 | E-GEOD-41716 | biostudies-arrayexpress
TranscriptomicsTranscription profiling of mouse uterus from _gravidl_d18 wild type vs. Cox-1 knockout animal
Background: Preterm birth is the leading cause of all infant mortality. In 2004, 12.5% of all births were preterm. In order to understand preterm labor, we must first understand normal labor. Since many of the myometrial changes that occur during pregnancy are similar in mice and humans and mous...
ORGANISM(S): Mus musculus 
2008-06-16 | E-GEOD-8269 | biostudies-arrayexpress
TranscriptomicsPluripotent embryonic stem cells and multipotent adult germline stem cells reveal similar transcriptomes including pluripotency-related genes
DNA microarray analysis was performed with mouse multipotent adult germline stem cells (maGSCs) and embryonic stem cells (ESCs) from different genetic backgrounds cultured under standard ESC culture conditions and under differentiation-promoting conditions by the withdrawal of Leukemia Inhibitory Fa...
ORGANISM(S): Mus musculus 
2010-07-12 | E-GEOD-22605 | biostudies-arrayexpress
TranscriptomicsInferring the stress-activated signaling network in yeast through multi-omic data integration
Transcriptome profiling of yeast mutant strains responding to 0.7M NaCl treatment for 30 minutes. This study identified affected genes in each mutant and used it to computationally infer the complete NaCl-activated signaling network in yeast. Two-color fluorescence arrays reporting on mRNA abundanc...
ORGANISM(S): Saccharomyces cerevisiae 
2014-12-03 | E-GEOD-51844 | biostudies-arrayexpress
TranscriptomicsGene expression characterization of HPV positive head and neck cancer to predict response to Chemoradiation
Background: Human papillomavirus has been shown to have a causal role in the development of head and neck squamous cell carcinoma and represents a distinct and well-defined pathology. While HPV-positive HNSCC is associated with a better response to treatment and prognosis, a subset of patients do no...
ORGANISM(S): Homo sapiens 
2014-12-19 | E-GEOD-40020 | biostudies-arrayexpress
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