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TranscriptomicsPACAP dependency of genes regulated in adrenal gland
We investigated the effects of PACAP knock out on the transcriptosome profile of adrenal gland. A 35,546-clone mouse cDNA microarray was used to investigate transcriptional changes Keywords: transcript identification design In the hybridization method employed, equal amounts (2-5 ug/15.5 ul) of tota...
ORGANISM(S): Mus musculus 
2010-05-26 | E-GEOD-7405 | biostudies-arrayexpress
TranscriptomicsEffect of PACAP treatment on Bovine chromaffin cells
The effect of PACAP treatment on the bovine chromaffin cells in vitro were investigated using mouse Mm36kd3 arrays. Although chromaffin cells have indigenous PACAP, the experiment was designed to find out the effect of additional PACAP on additional activation or suppression of transcription. Keywor...
ORGANISM(S): Bos taurus 
2010-05-26 | E-GEOD-7406 | biostudies-arrayexpress
TranscriptomicsPACAP dependency of genes regulated in ischemia
We investigated the effects of PACAP treatment, and endogenous PACAP deficiency, on infarct volume, neurological function, and the cerebrocortical transcriptional response in a mouse model of stroke, middle cerebral artery occlusion (MCAO). PACAP-38 administered i.v. or i.c.v. one hour after MCAO si...
ORGANISM(S): Mus musculus 
2010-07-01 | E-GEOD-5902 | biostudies-arrayexpress
TranscriptomicsPACAP and TNF regulate discrete population of genes in bovine chromaffin cells
The bovine chromaffin cell (BCC) is a unique modelM-bM-^@M-^Ta highly homogeneous and accessible neuroendocrine cellM-bM-^@M-^Tin which to study gene regulation through first messenger-initiated signaling pathways that are specific to post-mitotic cells. BCCs were treated with tumor necrosis factor ...
ORGANISM(S): Bos taurus 
2012-09-01 | E-GEOD-24070 | biostudies-arrayexpress
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