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TranscriptomicsDiscovery of the p53 targetome in MCF7 cells from RNA-seq and ChIP-seq data
This SuperSeries is composed of the SubSeries listed below. iRegulon: from a gene list to a gene regulatory network using large motif and track collections. RekinM-bM-^@M-^Ys Janky, Annelien Verfaillie, Hana ImrichovM-CM-!, Bram Van de Sande, Laura Standaert, Valerie Christiaens, Gert Hulselmans, ...
ORGANISM(S): Homo sapiens 
2014-05-27 | E-GEOD-47043 | biostudies-arrayexpress
MetabolomicsAmino Acid Metabolism is Significantly Altered at the Time of Admission in Hospital for Severe COVID-19 Patients: Findings from Longitudinal Targeted Metabolomics Analysis

The heterogeneity in severity and outcome of COVID-19 cases points out the urgent need for early molecular characterization of patients followed by risk-stratified care. The main objective of this study was to evaluate the fluctuations of serum metabolomic profiles of COVID-19 patients with sever...

2022-08-23 | MTBLS3852 | MetaboLights
TranscriptomicsFailures of nerve regeneration caused by aging or chronic denervation are rescued by restoring Schwann cell c-Jun
After nerve injury, myelin and Remak Schwann cells reprogram to repair cells specialized for regeneration. Normally providing strong regenerative support, these cells fail in aging animals, and during the chronic denervation that results from slow axon growth. This impairs axonal regeneration and ca...
ORGANISM(S): Mus musculus 
2020-10-14 | E-MTAB-9640 | biostudies-arrayexpress
TranscriptomicsOverexpression of c-Jun in mouse Schwann cells of uninjured nerves
Two mouse lines, OE/+ and OE/OE were generated expressing graded elevation (6 fold and 28 fold, respectively) of c-Jun protein selectively in Schwann cells. The effects of this on global gene expression and cellular structure in uninjured nerves was analysed during development and in the adult. Chan...
ORGANISM(S): Mus musculus 
2017-10-16 | E-MTAB-6138 | biostudies-arrayexpress
MetabolomicsGNPS - Molecular networking as a dereplication strategy -Figure 4
Molecular networking as a dereplication strategy. Yang JY, Sanchez LM, Rath CM, Liu X, Boudreau PD, Bruns N, Glukhov E, Wodtke A, de Felicio R, Fenner A, Wong WR, Linington RG, Zhang L, Debonsi HM, Gerwick WH, Dorrestein PC. J Nat Prod. 2013 Sep 27;76(9):1686-99. doi: 10.1021/np400413s PubMedID: 240...
ORGANISM(S): Data From Multiple Bacteria 
2014-02-11 | MSV000078547 | GNPS
MetabolomicsGNPS - Molecular networking as a dereplication strategy-Figure 3
Molecular networking as a dereplication strategy. Yang JY, Sanchez LM, Rath CM, Liu X, Boudreau PD, Bruns N, Glukhov E, Wodtke A, de Felicio R, Fenner A, Wong WR, Linington RG, Zhang L, Debonsi HM, Gerwick WH, Dorrestein PC. J Nat Prod. 2013 Sep 27;76(9):1686-99. doi: 10.1021/np400413s PubMedID: 24...
ORGANISM(S): Six Distinct Collections Of Cyanobacteria 
2014-02-11 | MSV000078548 | GNPS
ProteomicsCyclo(D-His,L-Pro) as a signaling molecule from V. fischeri
Investigation of host-microbe symbiosis, using both MALDI-TOF-IMS and LC-MS/MS.
ORGANISM(S): Vibrio Fischeri 
2020-04-23 | MSV000085327 | MassIVE
MetabolomicsBenthic exometabolites and their ecological significance on threatened Caribbean coral reefs (Metabolite collection incubation assays)

Benthic organisms sustain coral reefs through their growth and metabolism, but less is known about how their released metabolites influence reef seawater microorganisms. To investigate metabolite composition of benthic exudates and their ecological significance for reef microbial communities, we ...

2022-08-22 | MTBLS2855 | MetaboLights
UnknownCpG island methylator phenotype in adenocarcinomas from the digestive tract: Methods, conclusions, and controversies.
Not available
S-EPMC5348626 | biostudies-literature
ProteomicsFallopian tube secreted proteins affect ovarian metabolites in high grade serous ovarian cancer
Data files from Q Exactive were imported into Proteome Discoverer (version 2.2, Thermo Fisher) and analyzed using a label-free quantitation method. For MOE PTENshRNA protein IDs, MOE PTENshRNA results were compared to MOE SCRshRNA results against a Mus musculus database (10090_20160912 fasta file) a...
ORGANISM(S): Homo Sapiens (ncbitaxon:9606) Mus Musculus (ncbitaxon:10090) 
2022-07-11 | MSV000089866 | MassIVE
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