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MetabolomicsRegulatory T cells promote endurance exercise adaptation by shielding muscle mitochondria from damage

Exercise enhances physical performance and reduces the risk of many disorders such as cardiovascular disease, type 2 diabetes, dementia and cancer. Exercise characteristically incites an inflammatory response, notably in skeletal muscles. While some effector mechanisms have been identified, regul...

2023-10-10 | MTBLS8391 | MetaboLights
TranscriptomicsScRNA/TCR-seq of T cells from EMT6 tumors treated with aTGFb/aPD-L1
We performed 10x single cell RNA and VDJ sequencing on sorted T cells (7AAD- Calcein blue+ CD45+ THY1.1- TCRb+) in an orthotopic EMT6 tumor model 7 days after treatment initiation in four experimental groups: 1) Control 2) aPD-L1 3) aTGFb 4) aPD-L1 and aTGFb.
ORGANISM(S): Mus musculus 
2023-06-30 | E-MTAB-13073 | biostudies-arrayexpress
GenomicsBC Cancer, part of the Provincial Health Services Authority, Technology Development Office, Data Access Committee (PHSA TDO DAC)
Access to data generated by BCCA is made available by completing the data access agreement for review by the data access committee and will be granted to qualified investigators for appropriate use.
EGAC00000000011 | EGA
Genomicsena-DATASET-BCCA-13-11-2014-22:09:20:907-954 - samples
Dynamics of genomic clones in breast cancer patient xenografts at single cell resolution
EGAD00001001066 | EGA
GenomicsDynamics of genomic clones in breast cancer patient xenografts at single cell resolution
Human cancers, including breast cancers, are comprised of clones differing in mutation content that evolve dynamically in space and time following principles of Darwinian evolution, underpinning important emergent features such as drug resistance and metastasis. Human breast cancer xenoengraftment i...
EGAS00001000952 | EGA
UnknownSARS-CoV-2 Infection Depends on Cellular Heparan Sulfate and ACE2.
Not available
S-EPMC7489987 | biostudies-literature
UnknownSARS-CoV-2 infectivity can be modulated through bacterial grooming of the glycocalyx.
Not available
S-EPMC11980591 | biostudies-literature
UnknownGene content, phage cycle regulation model and prophage inactivation disclosed by prophage genomics in the <i>Helicobacter pylori</i> Genome Project.
Not available
S-EPMC11321410 | biostudies-literature
UnknownThe Effect of Incidental Consolidation on Management and Outcomes in COPD Exacerbations: Data from the European COPD Audit.
Not available
S-EPMC4516303 | biostudies-literature
UnknownA second update on mapping the human genetic architecture of COVID-19.
Not available
S-EPMC10482689 | biostudies-literature
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