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TranscriptomicsThe miR-146b-3p/PAX8/NIS Regulatory Circuit Modulates the Differentiation Phenotype and Function of Thyroid Cells During Carcinogenesis.
To comprehensively characterize microRNAs (miRNA) expression and their target genes in thyroid cancer, we performed next-generation sequencing expression analysis of this disease. Recent studies have found that only the most abundant microRNAs mediate significant target suppression. We sequenced sma...
ORGANISM(S): Homo sapiens 
2015-08-24 | E-GEOD-63511 | biostudies-arrayexpress
TranscriptomicsGenome wide profiling of FOXE1 binding sites in PCCL3 rat cells
FoxE1 transcriptional profiling of rat PCCL3 cells comparing wild type cells with FoxE1 silenced cells and scramble treated with FoxE1 silenced cells. Three-condition experiment, FoxE1 silenced vs. Wild type cells. Biological replicates: 4 replicates, 1pooled sample dye-swap. and FoxE1 silenced vs s...
ORGANISM(S): Rattus norvegicus 
2013-05-14 | E-GEOD-42497 | biostudies-arrayexpress
GenomicsGenome wide profiling of PAX8 binding stes in PCCL3 rat cells
Analysis of PAX8 binding sites by chromatin immunoprecipitation coupled with ultra-high-throughput sequencing (ChIP-seq) in PCCL3 rat cells. Results provide insight into the contribution of this regulatory factor to transcription genome-wide. We generate a genome wide map of PAX8 binding sites in PC...
ORGANISM(S): Rattus norvegicus 
2012-06-27 | E-GEOD-26871 | biostudies-arrayexpress
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