Sarcoglycan complex

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Proteomics (567)
Transcriptomics (132)
Unknown (62)
Multiomics (35)
Models (25)
Genomics (18)
Other (8)
Metabolomics (8)

Organisms

Homo sapiens (155)
Mus musculus (107)
Arabidopsis thaliana (17)
Caenorhabditis elegans (16)
Saccharomyces cerevisiae (5)
Drosophila melanogaster (4)
Danio rerio (4)
Sus scrofa (4)
Hordeum vulgare subsp. vulgare (3)
Oryza sativa Japonica Group (3)
Streptomyces venezuelae (2)
Solanum lycopersicum (2)
Nostoc sp. PCC 7120 = FACHB-418 (1)
Lathyrus sativus (1)
Pseudomonas protegens (1)
Schizophyllum commune (1)
Nothobranchius furzeri (1)
Pan troglodytes (1)
Phaeodactylum tricornutum (1)
Macaca fascicularis (1)
Porphyromonas gingivalis (1)
Schizosaccharomyces pombe (1)
mixed sample (1)
Saccharomyces cerevisiae S288C (1)
Salmonella enterica subsp. enterica serovar Typhimurium (1)
Solanum tuberosum (1)
Vibrio cholerae (1)
Heterocephalus glaber (1)
Mycobacterium tuberculosis H37Rv (1)
Escherichia coli K-12 (1)

Organisms

Mus musculus (4)

Repository

MassIVE (349)
biostudies-arrayexpress (141)
jPOST (104)
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iProX (32)
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geo (4)
ENA (4)
pride (2)
EVA (1)

Tissue

Others (26)
Male Reproductive System (8)
Female Reproductive System (7)
Spleen (3)
Liver (2)
Lung (1)
Pancreas (1)
Digestive System (1)
Kidney (1)
Muscle fibre (1)
Plasma membrane (1)
Gastrocnemius (1)
Skeletal muscle (1)
Tendon (1)

Disease

Autosomal recessive limb-girdle muscular dystrophy type 2C (1)

Technology Type

KINOMEscan (23)
Fluorescence intensity (23)
Mass spectrometry assay (7)
Mass Spectrometry (2)
Shotgun proteomics (2)
NMR spectroscopy (1)
Gel-based experiment (1)
Affinity purification coupled with mass spectrometry proteomics (1)

Instrument Platform

Illumina NovaSeq 6000 (51)
NextSeq 2000 (19)
Illumina NovaSeq X (15)
NextSeq 500 (13)
Illumina HiSeq 2500 (7)
DNBSEQ-G400 (4)
Illumina HiSeq 2000 (4)
Illumina HiSeq 4000 (4)
None (3)
NextSeq 550 (3)
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NA (2)
N/A (2)
DNBSEQ-T7 (2)
Illumina MiSeq (2)
Illumina NOVAseq 6000 (1)
Agilent TapeStation (1)
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FACS BD Aria II & III (1)
Using NEBNext Ultra II DNA Library (1)
NEBNext rRNA Depletion Kit v2 and NEBNext Ultra II Directional RNA Library Prep Kit Illumina kits (1)
Macbook Pro 2018 (1)
BRB-seq tool and pipeline (1)
NucleoSpin RNA kit (Macherey-Nagel) (1)
Gilson Minipuls 3 (1)
DNBSEQ Eukaryotic Stranded Transcriptome library preparation- Stranded mRNA Library (1)
KAPA EvoPrep Kit (1)
FastPrep-24 5G bead beater, Qubit Fluorometer (1)
12 well TC-treated plate, LETs buffer, dry ice (1)

Publication Date

2025 (101)
2026 (70)
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2016 (65)
2024 (61)
2021 (58)
2023 (54)
2019 (51)
2014 (51)
2020 (49)
2018 (30)
2017 (30)
2015 (21)
2013 (9)
2010 (2)
2012 (1)
2009 (1)
2008 (1)

UNIPROT ID/AC

Q13162 (50)
Q9BYX7 (50)
Q08043 (50)
Q00610-2 (50)
Q00610 (50)
P55072 (50)
P04792 (50)
P35609-2 (50)
P35609 (50)
P12814-3 (50)
P12814 (50)
Q58FF8 (50)
Q58FF7 (50)
Q58FF6 (50)
Q3ZCM7 (50)
Q13707 (50)
P68133 (50)
P68032 (50)
P63267 (50)
P62736 (50)
P54652 (50)
P35908 (50)
P34931 (50)
P17066 (50)
P13645 (50)
P11217 (50)
P11142 (50)
P11021 (50)
P0DMV8 (50)
P08729 (50)

ENSEMBL ID

ENSG00000170477 (43)
ENSG00000229353 (34)
ENSG00000147251 (18)
ENSG00000247315 (11)
ENSG00000204131 (3)
ENSG00000176092 (2)

CHEBI ID

CHEBI:40574 (1)
CHEBI:35366 (1)
CHEBI:23219 (1)
CHEBI:46996 (1)
CHEBI:3098 (1)
CHEBI:16830 (1)
CHEBI:18139 (1)
CHEBI:87986 (1)
CHEBI:17925 (1)
CHEBI:18009 (1)
CHEBI:27838 (1)
CHEBI:27410 (1)
CHEBI:17992 (1)
CHEBI:47925 (1)
CHEBI:18066 (1)
CHEBI:17200 (1)
CHEBI:64399 (1)
CHEBI:50129 (1)
CHEBI:15903 (1)
CHEBI:18132 (1)
CHEBI:15846 (1)
CHEBI:17858 (1)
CHEBI:16856 (1)
CHEBI:17126 (1)
CHEBI:18261 (1)
CHEBI:15753 (1)
CHEBI:30751 (1)
CHEBI:18186 (1)
CHEBI:26986 (1)
CHEBI:16811 (1)

Metabolite Name

Leucine (2)
1-O-((3.beta.,5.Xi.,9.Xi.,18.Xi.,19.Xi.,20.Xi.)-3-((6-Deoxyhexopyranosyl)oxy)-27-hydroxy-27,28-dioxours-12-en-28-yl)-6-O-hexopyranosylhexopyranose (1)
MCULE-7407861812 (1)
NCGC00381308-01 (1)
Ncgc00169736-02!(3r,5r)-3,4,5-tris[[(e)-3-(3,4-dihydroxyphenyl)prop-2-enoyl]oxy]-1-hydroxycyclohexane-1-carboxylic acid (1)
Medicagenic acid base -H2O + O-HexA (1)
2-[2-[(E)-(Isonicotinoylhydrazono)methyl]phenoxy]acetic acid (1)
5-(4-Hydroxyphenyl)-1-[2-(4-hydroxyphenyl)ethyl]pentyl 2-O-D-apio-.beta.-D-furanosyl-.beta.-D-glucopyranoside (1)
Kaempferol 3-glucoside 7-rhamnoside (1)
CHEMBL2326941 (1)
Chenodeoxycholic acid 24-acyl-.beta.-D-glucuronide (1)
Indigoticoside A (1)
12-Deoxyphorbol 13-laurate (1)
.beta.-Linoleoyl-.alpha.-glycerophosphorylcholine (1)
MGMG 18:2 (1)
CHEBI:139416 (1)
Liguiritigenin-7-O-beta-D-apiosyl-4'-O-beta-D-glucoside (1)
(3.beta.,5.Xi.,9.Xi.,18.Xi.)-3,19-Dihydroxyurs-12-ene-24,28-dioic acid (1)
17:0 Lyso PC (1)
Dilauroylphosphatidic acid (1)
SCHEMBL19999136 (1)
MEGxp0_001059 (1)
4-(4-(4-Hydroxy-3-methoxyphenyl)tetrahydro-1H,3H-furo[3,4-c]furan-1-yl)-2-methoxyphenyl hexopyranoside (1)
Maslic acid (1)
4,5-Di-O-caffeoylquinic acid (1)
3,5-Di-O-caffeoylquinic acid (1)
5-Hydroxy-1,7,7-trimethylbicyclo[2.2.1]heptan-2-yl 6-O-(3,4-dihydroxy-4-(hydroxymethyl)tetrahydrofuran-2-yl)hexopyranoside (1)
2-(4-Methylcyclohex-3-en-1-yl)propan-2-yl 6-O-(6-deoxy-.alpha.-L-mannopyranosyl)-.beta.-D-glucopyranoside (1)
23-Hydroxytormentic acid (1)
6-O-.beta.-D-Glucopyranosyl-1-O-((3.beta.,5.xi.,9.xi.)-3,19,24-trihydroxy-24,28-dioxours-12-en-28-yl)-.beta.-D-glucopyranose (1)

First Public Date

2025 (1)
2024 (1)
2015 (1)
2014 (1)

Study type

RNA-seq of coding RNA (61)
RNA-seq of coding RNA from single cells (27)
RNA-seq of total RNA (14)
Transcription profiling by array (9)
ChIP-seq (8)
ATAC-seq (3)
Methylation profiling by high throughput sequencing (3)
Unknown experiment type (2)
Spatial transcriptomics by high-throughput sequencing (2)
RIP-seq (2)
DNA-seq (2)
CUT&RUN (2)
MeDIP-seq (1)
MBD-seq (1)
MicroRNA profiling by high throughput sequencing (1)
Comparative genomic hybridization by array (1)
Ribo-seq (1)
RNA-seq of non coding RNA (1)

Release Date

2025 (70)
2026 (63)
2023 (6)
2022 (6)
2015 (6)
2016 (6)
2021 (5)
2014 (5)
2024 (4)
2012 (4)
2009 (4)
2020 (3)
2011 (3)
2010 (2)
2019 (2)
2018 (2)
2001 (2)
2013 (1)
2017 (1)
2008 (1)
2007 (1)
2006 (1)
2004 (1)
2000 (1)
1999 (1)
1998 (1)
1997 (1)

Lab affiliation

Department of Radiology, Division of Cell Biology & Imaging, University of Massachusetts Medical School, Worcester, MA, USA (1)
Novo Nordisk Center For Basic Metabolic Research, University of Copenhagen. (1)

Tags

xref:PubMed:40549548 (1)
xref:PubMed:18780762 (1)
xref:PubMed:38527667 (1)
xref:PubMed:25698924 (1)

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The Sarcoglycan complex is expressed in the cerebrovascular system and is specifically regulated by astroglial Cx30 channels

Astrocytes, the most prominent glial cell type in the brain, send specialized processes called endfeet around blood vessels and express a large molecular repertoire regulating the cerebrovascular system physiology. One of the most striking properties of astrocyte endfeet is their enrichment in gap j...

ORGANISM(S): Mus musculus

2015-03-03 | E-GEOD-59148 | biostudies-arrayexpress

Sarcoglycan interactions in murine muscle membranes

The sarcoglycan complex (SC) is part of a network that links the striated muscle cytoskeleton to the basal lamina across the sarcolemma. The SC coordinates changes in phosphorylation and Ca++-flux during mechanical deformation, and these processes are disrupted with loss-of-function mutations in gam...

ORGANISM(S): Mus musculus (Mouse)

2022-02-16 | PXD028584 | Pride

Sarcoglycan complex: implications for metabolic defects in muscular dystrophies.

Not available

S-EPMC2740540 | biostudies-literature

Sarcospan selectively interfaces with sarcoglycan subunits to stabilize the sarcolemma and prevent limb-girdle muscular dystrophy

Gene duplication events provide redundancy to complex organisms, and homologous genes and their encoded proteins are potential replacements to treat loss-of-function genetic syndromes. Skeletal muscle possesses redundant molecular mechanisms that partially or fully compensate for loss of gene functi...

ORGANISM(S): Mus musculus

2025-06-01 | GSE291423 | GEO

Sarcospan selectively interfaces with sarcoglycan subunits to stabilize the sarcolemma and prevent limb-girdle muscular dystrophy

PRJNA1233349 | ENA

The Sarcoglycan complex is expressed in the cerebrovascular system and is specifically regulated by astroglial Cx30 channels

ORGANISM(S): Mus musculus

2015-03-03 | GSE59148 | GEO

Myoclonus dystonia and muscular dystrophy: ɛ-sarcoglycan is part of the dystrophin-associated protein complex in brain.

Not available

S-EPMC5129563 | biostudies-literature

Sarcospan protects against LGMD R5 via remodeling of the sarcoglycan complex composition in dystrophic mice.

Not available