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MetabolomicsMouse model of sarcoma (STS) to characterize tumor vulnerabilities and identify novel targets for anti-cancer treatment
Not available
ORGANISM(S): Mus musculus 
ST001611 | MetabolomicsWorkbench
TranscriptomicsRUNX3 Facilitates Growth of Ewing Sarcoma Cells
Ewing sarcoma is an aggressive pediatric small round cell tumor that predominantly occurs in bone. Approximately 85% of Ewing sarcomas harbor the EWS/FLI fusion protein, which arises from a chromosomal translocation, t(11:22)(q24:q12). EWS/FLI interacts with numerous lineage-essential transcription...
ORGANISM(S): Homo sapiens 
2014-05-01 | E-GEOD-56900 | biostudies-arrayexpress
ProteomicsIlluminating phenotypic drug responses of sarcoma cells to kinase inhibitors by phosphoproteomics
Kinase inhibitors (KIs) are important cancer drugs but often display polypharmacology that is molecularly not understood. This disconnect is particularly apparent in cancer entities such as sarcomas for which the oncogenic drivers are often not clear. To investigate more systematically how the cellu...
ORGANISM(S): Homo Sapiens (ncbitaxon:9606) 
2023-01-11 | MSV000091043 | MassIVE
ProteomicsIlluminating phenotypic drug responses of sarcoma cells to kinase inhibitors by phosphoproteomics-2
Kinase inhibitors (KIs) are important cancer drugs but often display polypharmacology that is molecularly not understood. This disconnect is particularly apparent in cancer entities such as sarcomas for which the oncogenic drivers are often not clear. To investigate more systematically how the cellu...
ORGANISM(S): Homo Sapiens (ncbitaxon:9606) 
2023-11-29 | MSV000093533 | MassIVE
TranscriptomicsExpression data from human sarcoma patient samples treated with either vehicle control or Nutlin-3a
This study has examined the molecular mechanisms underlying sensitivity of sarcomas to Nutlin-3a, a non-genotoxic activator of the p53 pathway. Human patient material was collected immediately following surgical resection, dissected into small pieces and ex planted onto gelatin sponges immersed in m...
ORGANISM(S): Homo sapiens 
2014-03-10 | E-GEOD-48296 | biostudies-arrayexpress
TranscriptomicsTranscription profiling of human lymphatic endothelial cells response to Kaposi-sarcoma herpesvirus
Assessment of the effect of Kaposi-sarcoma herpesvirus upon the transcriptome of lymphatic endothelial cells and its contribution to the transcriptome of Kaposi sarcoma.
ORGANISM(S): Homo sapiens 
2006-10-23 | E-MEXP-561 | biostudies-arrayexpress
TranscriptomicsTranscription profiling of human Ewing sarcoma (A673) cells treated with cytarabine, doxorubicin and puromycin oral tongue squamous cell carcinomas to identify novel potential prognosticators
An increasing number of cancer-associated mutations have been identified. Unfortunately, little therapy today exploits these tumor-specific genetic lesions. Often, the resulting oncoproteins have been intractable to easy manipulation with current small molecule screening approaches. To overcome this...
ORGANISM(S): Homo sapiens 
2008-11-22 | E-GEOD-6930 | biostudies-arrayexpress
TranscriptomicsCD109 expression regulates the phenotype of cancer stem-like cells or cancer-initiating cells in epithelioid sarcoma with possible impact on clinical prognosis
Several human cancers contain a small subpopulation of cells called cancer stem-like cells (CSCs)/cancer initiating cells (CICs), which are defined by the ability of self- renewal, multi-differentiation potential, and tumorigenesis. In current study, we focused on epithelioid sarcoma, which is very ...
ORGANISM(S): Homo sapiens 
2014-01-07 | E-MEXP-3826 | biostudies-arrayexpress
UnknownA Critical Review of the Impact of Sarcoma on Psychosocial Wellbeing.
Not available
S-EPMC6397984 | biostudies-literature
TranscriptomicsTranscription profiling of Kaposi sarcoma, normal skin and primary cells
Identification of the relationships of Kaposi sarcoma (KS), normal skin to various cell cultures. The effects of KS herpes virus, the infectious cause of KS, on infected endothelial cells are also investigated.
ORGANISM(S): Homo sapiens 
2004-08-01 | E-MEXP-66 | biostudies-arrayexpress
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