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MetabolomicsMulti-omics association analysis reveals interactions between the oropharyngeal microbiome and the metabolome in pediatric patients with influenza A virus pneumonia.
Children are at high risk for influenza A virus (IAV) infections, which can develop into severe illnesses. However, little is known about interactions between the microbiome and respiratory tract metabolites and their impact on the development of IAV pneumonia in children. Using a combination of liq...
2024-09-25 | MTBLS4816 | MetaboLights
TranscriptomicsExpression profiling of Candida albicans and Candida dubliniensis in reconstituted human oral epithelium 30 min p.i.
Candida albicans and Candida dubliniensis are closely related species displaying differences in virulence and genome content, therefore providing potential opportunities to identify novel C. albicans virulence genes. C. albicans gene arrays were used for comparative analysis of global gene expressio...
ORGANISM(S): Candida albicans 
2010-05-16 | E-GEOD-13318 | biostudies-arrayexpress
TranscriptomicsTissue Specific Pathways for Estrogen Regulation of Ovarian Cancer Growth and Metastasis
Menopausal estrogen (E2) replacement therapy increases the risk of estrogen receptor (ER)-positive epithelial ovarian cancers (EOC). Whether E2 is tumorigenic or promotes expansion of undiagnosed pre-existing disease is unknown. To determine E2 effects on tumor promotion, we developed an intraperito...
ORGANISM(S): Homo sapiens 
2011-05-13 | E-GEOD-22600 | biostudies-arrayexpress
MetabolomicsLipopolysaccharides from Ralstonia solanacearum induce a broad metabolomic response in Solanum lycopersicum

Ralstonia solanacearum, one of the most destructive crop pathogens worldwide, causes bacterial wilt disease in a wide range of host plants. The major component of the outer membrane of Gram-negative bacteria, lipopolysaccharides (LPS), has been shown to function as elicitors of plant defense lead...

2023-08-08 | MTBLS7324 | MetaboLights
TranscriptomicsExpression profiling of Candida albicans and Candida dubliniensis in reconstituted human oral epithelium 90 min p.i.
Candida albicans and Candida dubliniensis are closely related species displaying differences in virulence and genome content, therefore providing potential opportunities to identify novel C. albicans virulence genes. C. albicans gene arrays were used for comparative analysis of global gene expressio...
ORGANISM(S): Candida dubliniensis 
2010-05-16 | E-GEOD-13345 | biostudies-arrayexpress
MetabolomicsCardiac untargeted lipidomics in cardiomyocyte-specific Srebp1a-Tg mice

Background: Heart failure with reduced ejection fraction (HFrEF) is characterized by impaired contractility and high mortality. Dysregulation of intracellular ion cycling underlies the decline in cardiac contractility. Modulation of cardiac Na+/H+ and Ca2+ handling is consider...

2026-02-20 | MTBLS13690 | MetaboLights
MetabolomicsUntargeted metabolomics as a hypothesis-generation tool in plant protection product discovery: Highlighting the potential of trehalose and glycerol metabolism of fungal conidiospores as novel targets

INTRODUCTION: The production of high quality and safe food represents a main priority for the agri-food sector in the effort to sustain the exponentially growing human population. Nonetheless, there are major challenges that require the discovery of new, alternative, and improved...

2020-09-08 | MTBLS1565 | MetaboLights
ProteomicsPhosphatidic acid features double membrane vesicle formation during Hepatitis C and SARS-CoV-2 infection
Double membrane vesicles (DMVs) are used as replication organelles by pathogenic RNA viruses such as hepatitis C virus (HCV) and severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2). Viral DMVs are morphologically analogous to DMVs formed during autophagy, and although the proteins required...
ORGANISM(S): Homo sapiens (Human) 
2022-01-24 | PXD029692 | Pride
Dmvs Lipid phosphatidic acid Sars-cov-2 Hepatitis c 
ProteomicsAntibody microarray profiling of pancreatic cancer using 12 urine samples
Antibody microarray based profiling of twelve urine samples.
3 healthy female
3 heatlhy male
3 female with pancreatic cancer
3 male with pancreatic cancer
ORGANISM(S): Homo sapiens 
2012-05-03 | E-MEXP-3006 | biostudies-arrayexpress
UnknownDevelopment of a high-throughput solubility screening assay for use in antibody discovery.
Not available
S-EPMC6601704 | biostudies-literature
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