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TranscriptomicsGene expression analysis of diabetic kidney cortices obtained from ICAM-1 deficient mice and wild type mice.
In the present study, we aimed to determine the genes involved in inflammatory process of diabetic nephropathy. ICAM-1+/+ and ICAM-1-/- mice aged 8 weeks were divided into four groups: 1) nondiabetic ICAM-1+/+ mice (ND-WT), 2) nondiabetic ICAM-1-/- mice (ND-KO), 3) streptozotocin (STZ)-induced diab...
ORGANISM(S): Mus musculus 
2014-10-08 | E-GEOD-21390 | biostudies-arrayexpress
ProteomicscAMP/PKA signaling phosphorylates LRBA in renal collecting duct
Vasopressin/cAMP/protein kinase A (PKA)/aquaporin-2 (AQP2) water channels signaling in the kidneys is a canonical pathway that determines AQP2 activity in response to body fluid balance. AQP2 phosphorylation by PKA increases water reabsorption from urine for the prevention of further water loss. We...
ORGANISM(S): Mus musculus (Mouse) 
2022-07-23 | PXD033852 | Pride
Pka substrates Aqp2 Lrba Renal collecting duct 
ProteomicsMass spectrometry-based analysis of LRBA phosphorylation
Vasopressin/cAMP/protein kinase A (PKA) signaling phosphorylates AQP2 water channels in renal collecting ducts to reabsorb water from urine for the prevention of further water loss. Lipopolysaccharide-responsive and beige-like anchor protein (LRBA) mediates vasopressin-induced AQP2 phosphorylation; ...
ORGANISM(S): Mus musculus (Mouse) 
2022-07-23 | PXD033859 | Pride
Lrba Pka Vasopressin 
UnknownIpragliflozin and sitagliptin differentially affect lipid and apolipoprotein profiles in type 2 diabetes: the SUCRE study.
Not available
S-EPMC10854175 | biostudies-literature
UnknownPractical "1-2-3-4-Day" Rule for Starting Direct Oral Anticoagulants After Ischemic Stroke With Atrial Fibrillation: Combined Hospital-Based Cohort Study.
Not available
S-EPMC9022681 | biostudies-literature
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