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ProteomicsIdentification of alpha-satellite RNA interacting proteins
We set out to identify proteins that bind alpha-satellite ncRNAs in HCT-116 and SW-480 colorectal cancer human cell lines. We performed RNA pulldown followed by mass spectrometry identification of the associated proteins. Among the identified proteins, we observed a statistical overrepresenttion of ...
ORGANISM(S): Homo sapiens (Human) 
2022-08-12 | PXD024582 | Pride
Rna pulldown Ncrna Alpha satellite 
TranscriptomicsFibronectin regulates Wnt7a signaling and satellite cell expansion
The influence of the extracellular matrix (ECM) within the stem cell niche remains poorly understood. We found that Syndecan-4 (Sdc4) and Frizzled-7 (Fzd7) form a coreceptor complex in satellite cells and that binding of the ECM glycoprotein Fibronectin (FN) to Sdc4 stimulates the ability of Wnt7a t...
ORGANISM(S): Mus musculus 
2014-07-11 | E-GEOD-59272 | biostudies-arrayexpress
TranscriptomicsA Pitx2-miRNA pathway modulates cell proliferation in myoblasts and skeletal-muscle satellite cells and promotes their commitment to a myogenic cell fate.
The acquisition of a proliferating cell status from a quiescent state as well as the shift between proliferation and differentiation are key developmental steps in skeletal-muscle stem cells (satellite cells) to provide proper muscle regeneration. However, how satellite-cell proliferation is regulat...
ORGANISM(S): Mus musculus 
2015-06-10 | E-GEOD-53943 | biostudies-arrayexpress
TranscriptomicsRNA-seq from myogenic satellite cells from a translational porcine model for Duchenne muscular dystrophy, heterozygous female carriers, and their healthy wild-type counterpart
Satellite cells (SCs), the stem cell population of skeletal muscle, are crucial for growth and regeneration, and their dysfunction is increasingly recognized as a contributing factor to Duchenne muscular dystrophy (DMD). DMD is a severe, X-linked disorder caused by DMD gene mutations, leading to lo...
ORGANISM(S): Sus scrofa 
2025-12-11 | E-MTAB-16179 | biostudies-arrayexpress
TranscriptomicsRNA-Sequencing of primary myoblasts from mice with a satellite cell specific knockout of the histone demthylase UTX/KDM6A
The KDM6 histone demethylases (UTX/KDM6A and JMJD3/KDM6B) mediate removal of repressive histone H3K27me3 marks to establish transcriptionally permissive chromatin. Loss of UTX in female mice is embryonic lethal. Unexpectedly, male UTX-null mice escape embryonic lethality due to expression of UTY, a ...
ORGANISM(S): Mus musculus 
2016-03-22 | E-GEOD-69968 | biostudies-arrayexpress
TranscriptomicsTranscription profiling of mouse satellite cells isolated from skeletal muscle
(Abstract of publication submitted currently) To clarify molecular regulation of satellite cells, we performed genome-wide gene expression analysis of quiescent satellite cells isolated from mouse skeletal muscle by flow cytometry. We identified 53 novel quiescent satellite cell-specific genes whos...
ORGANISM(S): Mus musculus 
2008-06-12 | E-GEOD-3483 | biostudies-arrayexpress
TranscriptomicsExpression data of satellite cells through muscle injury time course
Satellite cells are resident skeletal muscle stem cells responsible for muscle maintenance and repair. In resting muscle, satellite cells are maintained in a quiescent state. Satellite cell activation induces the myogenic commitment factor, MyoD, and cell cycle entry to facilitate transition to a ...
ORGANISM(S): Mus musculus 
2012-07-31 | E-GEOD-38870 | biostudies-arrayexpress
GenomicsTurnip crinkle virus satellite RNA
Turnip crinkle virus satellite RNA overview
PRJNA69577 | ENA
TranscriptomicsWT and AUF1 KO satellite cell RNA-sequencing
Following skeletal muscle injury, muscle stem cells (satellite cells) are activated, proliferate, and differentiate to form myofibers. We show that mRNA decay protein AUF1 regulates satellite cell function through targeted degradation of specific mRNAs. AUF1 targets certain mRNAs containing 3 AU-...
ORGANISM(S): Mus musculus 
2016-07-21 | E-GEOD-83555 | biostudies-arrayexpress
TranscriptomicsExpression data during plantaris muscle hypertrophy with/without satellite cells induced by synergist ablation in young adult Pax7-DTA mice
Global gene expression patterns were determined from microarray results from sham surgery or following 1 week of plantaris muscle hypertrophy induced by synergist ablation in young adult Pax7-DTA mice (4 months). Vehicle treated mice have their full complement of satellite cells; tamoxifen treated m...
ORGANISM(S): Mus musculus 
2014-02-20 | E-GEOD-52597 | biostudies-arrayexpress
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