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TranscriptomicsExpression data from female reproductive organs of adult mice treated with estrogen
Estrogen induce organ-specific cell proliferation and development in female reproductive organs, though the reproductive differentiation, sex maturation, implantation and lactation. However, the mechanism of organ-specific estrogen responsive genes is unknown. Thus, we examined early estrogen respon...
ORGANISM(S): Mus musculus 
2007-02-06 | E-GEOD-6931 | biostudies-arrayexpress
TranscriptomicsDownregulation of the Wnt antagonist Dkk2 links loss of Sept4 and myofibroblastic transformation of hepatic stellate cells
Background/Aims: Sept4, a subunit of the septin cytoskeleton specifically expressed in quiescent hepatic stellate cells (HSCs), is downregulated through transdifferentiation to fibrogenic and contractile myofibroblastic cells. Since Sept4?/? mice are prone to liver fibrosis, we examined the unknown ...
ORGANISM(S): Mus musculus 
2012-06-02 | E-GEOD-24588 | biostudies-arrayexpress
ProteomicsRetinal-cysteine adduct in Opn5L1
Targeted analysis of retinal-cysteine adduct in Opsin 5 like-1 (Opn5L1) protein Chicken Opn5L1 E177K/Q192K mutant was expressed in HEK293T, regenerated by all-trans-retinal, solubilized by dodecyl maltoside, and purified using Rho1D4 antibody-conjugated Sephalose. Semi-quantitative targeted analyses...
ORGANISM(S): Gallus Gallus 
2018-02-15 | PXD008890 | JPOST Repository
ProteomicsSecretome analysis to elucidate metalloprotease-dependent ectodomain shedding of glycoproteins during neuronal cells differentiation
N1E-115 cells were seeded two days before sample preparation, and cultured in fresh medium containing 2% fetal bovine serum for 12 h before sample preparation. Cells were washed with serum-free medium for three times, and cultured in fresh serum-free DMEM with or without 50 μM GM6001 for 9 h. The co...
ORGANISM(S): Mus Musculus (mouse) 
2017-01-15 | PXD004699 | JPOST Repository
TranscriptomicsTranscription profiling by array of mouse oviduct, uterus and vagina treated with DES from new born mice to understand the mechanism of the differentiation of female reproductive tracts
Diethylstilbestrol (DES) inhibits the differentiation of female reproductive tracts during fetal and neonatal days . We examined global gene expressions in the oviduct, uterus and vagina in newborn mice with or without DES. These results suggest understanding the mechanism of the differentiation of...
ORGANISM(S): Mus musculus 
2004-10-28 | E-GEOD-1886 | biostudies-arrayexpress
TranscriptomicsTranscriptome analysis of the shoots of Arabidopsis wild-type and ammonium-insensitive mutant plants grown under 10 mM ammonium as sole nitrogen source
Abundant ammonium nutrition impairs plant growth, i.e. ammonium toxicity, the primary cause of which remains to be determined. To obtain a clue about the toxic mechanism, we performed microarray experiments and compared the expression of genes responsive to toxic levels of ammonium between the wild-...
ORGANISM(S): Arabidopsis thaliana 
2021-07-24 | E-MTAB-10796 | biostudies-arrayexpress
GenomicsCopy number analysis of Diamond-Blackfan Anemia (DBA) using SNP array
Diamond–Blackfan anemia (DBA), is a rare congenital anemia that usually presents in infancy. About fifty percent of DBA patients possess mutations in ribosomal protains (RPs). In this study, we performed genomic copy number analysis using SNP arrays for 27 Japanese DBA patients to detect genomic c...
EGAS00000000105 | EGA
GenomicsDBA_250K - samples
DBA case samples using 250K Nsp
EGAD00010000096 | EGA
GenomicsCancer Genomics Project DBA Data Access Committee
Data Access Committee EGAC01000000005
EGAC01000000005 | EGA
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