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UnknownRandomized phase 3 trial of ombitasvir/paritaprevir/ritonavir for hepatitis C virus genotype 1b-infected Japanese patients with or without cirrhosis.
Not available
S-EPMC5049673 | biostudies-literature
TranscriptomicsGenome-wide survey of large rare copy number variations in Alzheimer’s disease among Caribbean Hispanics
Recently genome-wide association studies have identified significant association between Alzheimer’s disease and variations in CLU, PICALM, BIN1, CR1, MS4A4/MS4A6E, CD2AP, CD33, EPHA1 and ABCA7. However, the pathogenic variants in these loci have not yet been found. We conducted a genome-wide scan f...
ORGANISM(S): Homo sapiens 
2012-04-30 | E-GEOD-33528 | biostudies-arrayexpress
MetabolomicsA general non-self response as part of plant immunity
Plants, like other multicellular lifeforms, are colonized by microorganisms. How plants respond to their microbiota is currently not well understood. We used a phylogenetically diverse set of 39 endogenous bacterial strains from Arabidopsis thaliana leaves to assess host transcriptional and metaboli...
2021-09-13 | MTBLS2522 | MetaboLights
TranscriptomicsHuman intestinal tissue with adult stem cell properties derived from pluripotent stem cells
Genetically engineered human pluripotent stem cells (hPSCs) have been proposed as a source for transplantation therapies and are rapidly becoming valuable tools for human disease modeling. However, many of the potential applications are still limited by the lack of robust differentiation paradigms t...
ORGANISM(S): Homo sapiens 
2014-04-24 | E-GEOD-56930 | biostudies-arrayexpress
TranscriptomicsMisprocessing of APP and accumulation of β-Amyloid causes early alteration of pathways implicated in late-onset Alzheimer disease.
Genome-wide association studies (GWAS) have identified genes in lipid metabolism,inflammation and vesicular trafficking pathways as risk factors for late onset Alzheimer disease (LOAD). The mechanism by which they cause AD and their relationship to the amyloid cascade affected by genes causing early...
ORGANISM(S): Mus musculus 
2014-08-12 | E-GEOD-31372 | biostudies-arrayexpress
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