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TranscriptomicsTranscription profiling of mouse mK4 cell line that represents later metanephric mesenchyme of the embryonic kidney to identify Six1 and Six4 target genes
To identify Six1 target genes, we chose the mK4 cell line that represents later metanephric mesenchyme of the embryonic kidney. The cells were infected with adenovirus vectors (AxCAwt) overexpressing VP16-Six1wt or VP16-Six1W171R and cultured for 24h. Total RNA was extracted using Isogen reagent (Ni...
ORGANISM(S): Mus musculus 
2009-05-13 | E-GEOD-2043 | biostudies-arrayexpress
TranscriptomicsSphere-Derived Multipotent Progenitor Cells Obtained From Human Oral Mucosa Are Enriched in Neural Crest Cells.
The purpose of this study was to isolate NCSCs from oral mucosa using the neurosphere technique. Total RNA from human oral mucosa stromal cells and sphere-formig oral mucosa stromal cells was collected and compared at their gene expression level. Samples from 3 patients were analysed.
ORGANISM(S): Homo sapiens 
2016-07-03 | E-GEOD-68636 | biostudies-arrayexpress
TranscriptomicsIdentification of Myt1 as a subunit of the neural cell type-specific LSD1 complex
Regulation of spatiotemporal gene expression in higher eukaryotic cells is critical for the precise and orderly development of undifferentiated progenitors into committed cell types of the adult. Recently, dynamic epigenomic regulation, including chromatin remodeling and histone modifications by tra...
ORGANISM(S): Mus musculus 
2014-05-20 | E-GEOD-49685 | biostudies-arrayexpress
TranscriptomicsThe induced APL cells generated by the transplantation of PML-RARA-transduced human CD34+ hematopoietic cells into immunodeficient mice
A humanized in vivo APL model has been established utilizing the retroviral transduction of PML-RARA into human CD34+ hematopoietic cells and the transplantation of these cells into immunodeficient mice. The resultant leukemia recapitulated human APL phenotypically, and was clustered in the same cat...
ORGANISM(S): Homo sapiens 
2014-11-04 | E-GEOD-49344 | biostudies-arrayexpress
UnknownGermline variants and mosaic chromosomal alterations affect COVID-19 vaccine immunogenicity.
Not available
S-EPMC11960526 | biostudies-literature
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