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TranscriptomicsTranscription profiling of mouse Trib1-deficient animals vs controls
The purpose of this experiment was to compare the gene expression pattern between wild-type and Trib1-deficient macrophages in response to LPS. Experiment Overall Design: Two samples to define LPS-inducible gene and 4 samples (2 for wild-type and the rests for Trib1-deficient mice) for comparison.
ORGANISM(S): Mus musculus 
2008-11-06 | E-GEOD-8788 | biostudies-arrayexpress
TranscriptomicsTranscription profiling of Kawasaki disease patients who may benefit from methylprednisolone
Clinical score and transcript abundance patterns identify Kawasaki disease patients who may benefit from addition of methylprednisolone. Intravenous immunoglobulin (IVIG) treatment-resistant patients are high risk of developing coronary artery lesions (CALs) with Kawasaki disease (KD). The IVIG-resp...
ORGANISM(S): Homo sapiens 
2010-07-08 | E-GEOD-16797 | biostudies-arrayexpress
TranscriptomicsArray CGH data of A. oryzae strains bearing targeted tandem chromosomal duplications
We here describe the first successful construction of a targeted tandem duplication of a large chromosomal segment in Aspergillus oryzae. The targeted tandem chromosomal duplication was achieved by using strains that had 5M-bM-^@M-^YM-NM-^TpyrG upstream of the region targeted for tandem chromosomal ...
ORGANISM(S): Aspergillus oryzae RIB40 
2014-06-30 | E-GEOD-57246 | biostudies-arrayexpress
TranscriptomicsThe transcription repressors Bach2 and Bach1 promote B cell development by repressing the myeloid program
Mature lymphoid cells express the transcriptional repressor Bach2, which imposes regulation on humoral and cellular immunity. Here we found critical roles for Bach2 in the development of cells of the B lineage, commencing from the common lymphoid progenitor (CLP) stage, with Bach1 as an auxiliary. O...
ORGANISM(S): Mus musculus 
2014-10-26 | E-GEOD-61409 | biostudies-arrayexpress
TranscriptomicsTranscription profiling of mouse wild-type, TBK1, IKKi(Ikbke), or TBK1 IKKi doubly deficient embryonic fibroblats to elucidate how TBK1 and/or IKKi mediates B-DNA-mediated innate immune responses
B-DNA-induced gene expression profile in wild-type, TBK1, IKKi(Ikbke), or TBK1 IKKi doubly deficient embryonic fibroblats; to elucidate how TBK1 and/or IKKi mediates B-DNA-mediated innate immune responses. Experiment Overall Design: Total RNA was extracted from embryonic fibroblats transfected for 4...
ORGANISM(S): Mus musculus 
2007-12-07 | E-GEOD-4171 | biostudies-arrayexpress
ProteomicsHuman serum proteome of low-dose radiation area
Two sampling areas were focused in this study; Tande tande hamlet as high-level natural background radiation area (HBRA) and Topoyo sub-district as normal level background radiation area (NBRA), which was done under coordination with Local Health Office. The former located in 2° 44’ 38.3’’ south lat...
ORGANISM(S): Homo Sapiens (human) 
2022-05-12 | PXD025946 | JPOST Repository
TranscriptomicsHeLa cells consist of two cell types, as evidenced by cytochemical staining for alkaline phosphatase activity: A possible model for cancer stem cell study
Alkaline phosphatase (ALP) is known to be a marker for several somatic stem cells and cancer cells. We found that human squamous cell carcinoma HeLa cells are comprised by ALP-positive and negative cells. Single cell-derived colony assay revealed that the former cells are labile with respect to ALP ...
ORGANISM(S): Homo sapiens 
2013-04-23 | E-GEOD-42222 | biostudies-arrayexpress
TranscriptomicsExpression data from Evi1-transduced primary bone marrow cells
Evi1 is essential for proliferation of hematopoietic stem cells and implicated in the development of myeloid disorders. Particularly, high Evi1 expression defines one of the largest clusters in acute myeloid leukemia and is significantly associated with extremely poor prognosis. Improvement of the t...
ORGANISM(S): Mus musculus 
2010-07-08 | E-GEOD-22434 | biostudies-arrayexpress
ProteomicsProteome analysis of liver samples associated with cancer cachexia_sex
We analyzed samples from multiple mouse cancer cacheixa modles by quantitative proteomics.
ORGANISM(S): Mus Musculus (mouse) 
2023-08-04 | PXD042807 | JPOST Repository
ProteomicsProteome analysis of muscle, liver, and blood samples associated with cancer cachexia
We analyzed samples from multiple mouse cancer cacheixa modles and human gastric cancer patients by quantitative proteomics and protein acylation profiling.
ORGANISM(S): Homo Sapiens (human) Mus Musculus (mouse) 
2023-08-04 | PXD035832 | JPOST Repository
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