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TranscriptomicsIdentification of genes differentially expressed in lung cancer cells after the transfection of miR-221 or miR-222.
To evaluate involvement of miR-221 and miR-222 in lung cancer, we investigated the effects of miR-221 and miR-222 overexpression on six lung cancer cell lines as well as one immortalized normal human bronchial epithelial cell line. Two cell lines, H3255 and H1299 with no replicates were studied. Ce...
ORGANISM(S): Homo sapiens 
2015-05-22 | E-GEOD-57676 | biostudies-arrayexpress
TranscriptomicsTranscription profiling of lung cancer cells treated with 5-aza - a genome-wide screen for hypermethylated genes in lung cancer
Abstract; Background: Promoter hypermethylation coupled with loss of heterozygosity at the same locus results in loss of gene function in many tumor cells. The “rules” governing which genes are methylated during the pathogenesis of individual cancers, how specific methylation profiles are init...
ORGANISM(S): Homo sapiens 
2008-06-14 | E-GEOD-5816 | biostudies-arrayexpress
TranscriptomicsMethylation profiling of human NSCLC promoter regions identifies novel methylation markers for multiple malignancies
BACKGROUND: Promoter hypermethylation coupled with loss of heterozygosity at the same locus results in loss of gene function in many tumor cells. The "rules" governing which genes are methylated during the pathogenesis of individual cancers, how specific methylation profiles are initially establishe...
ORGANISM(S): Homo sapiens 
2008-06-15 | E-GEOD-6695 | biostudies-arrayexpress
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