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TranscriptomicsThe induced APL cells generated by the transplantation of PML-RARA-transduced human CD34+ hematopoietic cells into immunodeficient mice
A humanized in vivo APL model has been established utilizing the retroviral transduction of PML-RARA into human CD34+ hematopoietic cells and the transplantation of these cells into immunodeficient mice. The resultant leukemia recapitulated human APL phenotypically, and was clustered in the same cat...
ORGANISM(S): Homo sapiens 
2014-11-04 | E-GEOD-49344 | biostudies-arrayexpress
UnknownAcetamiprid Accumulates in Different Amounts in Murine Brain Regions.
Not available
S-EPMC5086676 | biostudies-literature
TranscriptomicsGene expression Tet-mev-1 mouse fed either normal diet or high fat high sucrose diet compared with wild type mouse
To assess the effect of steatosis and oxidative stress on progression of liver fibrosis, we have employed whole genome microarray expression profiling as a discovery platform to identify genes that are related with oxidative stress- and steatosis-induced hepatic fibrogenesis. When wild type mice wer...
ORGANISM(S): Mus musculus 
2015-05-07 | E-GEOD-68632 | biostudies-arrayexpress
TranscriptomicsGene expression profile induced by Imatinib
Activation-induced cytidine deaminase (AID) is essential for class switch recombination (CSR) and somatic hypermutation (SHM). Its deregulated expression acts as a genomic mutator that can contribute to the development of various malignancies. During treatment with imatinib mesylate (IM), patients w...
ORGANISM(S): Mus musculus 
2012-02-08 | E-GEOD-35559 | biostudies-arrayexpress
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