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TranscriptomicsRNA-seq of human monocytic cell line (THP-1) treated with compound #42 (2D216), LPS, #42(2D216)/LPS, or vehicle controls
To explore the effects of compound #42 on RNA transcription of THP-1 cells, we performed RNA-seq analysis.
ORGANISM(S): Homo sapiens 
2022-01-12 | E-MTAB-10222 | biostudies-arrayexpress
TranscriptomicsEffect of Lactobacillus brevis 119-2 isolated from turnip M-bM-^@M-^\Tsuda kabuM-bM-^@M-^] on hepatic cholesterol level in cholesterol-administrated rat
In previous in vitro study, we reported potential mechanism of cholesterol-lowering effect of Lactobacillus brevis119-2 (119-2) isolated from turnip M-bM-^@M-^\Tsuda kabuM-bM-^@M-^] is due to incorporation of cholesterol into 119-2 cell. In this study, we analyzed serum cholesterol and hepatic gene ...
ORGANISM(S): Rattus norvegicus 
2013-04-24 | E-GEOD-41734 | biostudies-arrayexpress
TranscriptomicsRNA-seq of human monocytic cell line (THP-1) treated with compound 81 or vehicle controls
To explore the effects of compound 81 on RNA transcription of THP-1 cells, we performed RNA-seq analysis.
ORGANISM(S): Homo sapiens 
2021-12-14 | E-MTAB-10269 | biostudies-arrayexpress
TranscriptomicsCD109 expression regulates the phenotype of cancer stem-like cells or cancer-initiating cells in epithelioid sarcoma with possible impact on clinical prognosis
Several human cancers contain a small subpopulation of cells called cancer stem-like cells (CSCs)/cancer initiating cells (CICs), which are defined by the ability of self- renewal, multi-differentiation potential, and tumorigenesis. In current study, we focused on epithelioid sarcoma, which is very ...
ORGANISM(S): Homo sapiens 
2014-01-07 | E-MEXP-3826 | biostudies-arrayexpress
TranscriptomicsDevelopment of mRNA and lincRNA expression signatures of MEFs deficient in ER stress mediators for tunicamycin treatment
To further development of our mRNA or lincRNA expression approach to ER stress, we have employed whole genome microarray expression profiling as a discovery platform to identify ER stress-responsible genes. Mouse embryonic fibroblasts (MEFs) deficient in each ER stress mediator (XBP1, ATF4, ATF6a ...
ORGANISM(S): Mus musculus 
2015-01-18 | E-GEOD-35173 | biostudies-arrayexpress
ProteomicsProteome analysis of wild-type and two heavy-ion beam-induced mutants of green alga Medakamo hakoo
Proteome analysis of total proteins extracted from wild-type and two heavy-ion beam-induced mutants of green alga M. hakoo using LC-MS/MS.
ORGANISM(S): Cellular Organisms 
2025-12-27 | PXD070625 | JPOST Repository
ProteomicsTMT-based quantitative proteomics in Rab35 cKO P0 hippocampus
The hippocampi from the control (Rab35flox/+; Nestin-Cre) and Rab35 cKO mice groups at P0 (n = 5 biological replicates per genotype) were lysed in a buffer containing 6 M guanidine hydrochloride, 100 mM HEPES-NaOH (pH 8.0), 10 mM TCEP, and 40 mM chloroacetamide. The lysates were dissolved through he...
ORGANISM(S): Mus Musculus (mouse) 
2023-04-07 | PXD041290 | JPOST Repository
TranscriptomicsGene expression profile of ATF6a and ATF6b knockout mice with dextran sulfate sodium (DSS)-induced colitis
To understand the role of ATF6a and ATF6b in non-canonical endoplasmic reticulum stress response pathway, we have employed whole genome microarray expression profiling to identify the genes regulated by ATF6s. WIild type or, ER stress mediators,ATF6a or ATF6b-knockout mice were treated with 3% DSS ...
ORGANISM(S): Mus musculus 
2015-02-08 | E-GEOD-35651 | biostudies-arrayexpress
ProteomicsSerum proteome profiling of patients with non-small cell lung cancer treated with immune checkpoint blockade monotherapy
Shotgun proteomic profiling of serum from patients with non-small cell lung cancer (NSCLC) treated with immune checkpoint blockade (ICB) monotherapy. Top-14 abundant proteins were depleted (Pierce High-Select, Thermo Fisher Scientific), and tryptic digests were spiked with the Pierce Peptide Retenti...
ORGANISM(S): Homo Sapiens (human) 
2026-06-10 | PXD078247 | JPOST Repository
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