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GenomicsSaturation mutagenesis of disease-associated regulatory elements
Saturation mutagenesis of disease-associated regulatory elements
PRJNA522353 | ENA
GenomicsSite saturation mutagenesis of 500 human protein domains
Site saturation mutagenesis of 500 human protein domains
PRJNA1105013 | ENA
GenomicsSaturation mutagenesis reveals manifold determinants of exon definition
Saturation mutagenesis reveals manifold determinants of exon definition
PRJNA415408 | ENA
Genomics
Saturation Mutagenesis of MlaC
PRJNA849600 | ENA
UnknownPlasmid-based one-pot saturation mutagenesis.
Not available
S-EPMC5666567 | biostudies-literature
OtherSaturation mutagenesis of disease-associated regulatory elements
The majority of common variants associated with common diseases, as well as an unknown proportion of causal mutations for rare diseases, fall in noncoding regions of the genome. Although catalogs of noncoding regulatory elements are steadily improving, we have a limited understanding of the function...
ORGANISM(S): Mus musculus Homo sapiens 
2019-02-15 | GSE126550 | GEO
Genomics
Stabilizing proteins through saturation suppressor mutagenesis
PRJNA766786 | ENA
UnknownHighly efficient libraries design for saturation mutagenesis.
Not available
S-EPMC9205323 | biostudies-literature
GenomicsSaturation mutagenesis of the human 5S rRNA gene defines expression- and ribosome-incorporation-defective variants
Saturation mutagenesis of the human 5S rRNA gene defines expression- and ribosome-incorporation-defective variants
PRJNA1499145 | ENA
OtherSaturation mutagenesis reveals manifold determinants of exon definition
To illuminate the extent and roles of exonic sequences in the splicing of human RNA transcripts we conducted saturation mutagenesis of a 51 nt internal exon in a 3-exon minigene. All possible single and tandem dinucleotide substitutions were surveyed. Using high throughput genetics, 5560 minigene mo...
ORGANISM(S): Homo sapiens 
2017-11-27 | GSE105785 | GEO
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