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TranscriptomicsRNA-Seq of human K-562 leukaemia cell line with and without K700E mutation in coding region of SF3B1 gene
The aim of this experiment was to compare the transcriptomes of SF3B1 mutant and wildtype isogenic cells at the whole cell, nuclear and cytoplasmic levels. Mutations in SF3B1 are often found in the malignant cells of patients suffering from myelodysplastic syndromes and more rarely in other cancer t...
ORGANISM(S): Homo sapiens 
2019-02-25 | E-MTAB-7192 | biostudies-arrayexpress
TranscriptomicsTranscription profiling by array of human MCF10A cells reveal changes upon expression of activated versions of MEK1 and HRAS
MCF10A cells were then transfected with MEK1(S217S221), HRAS(G12V), and null control vectors; Cells were lysed 24 hours post-transfection with collection of total RNA and protein Experiment Overall Design: Overexpression of Oncogenic protein was confirmed via Western blot
ORGANISM(S): Homo sapiens 
2009-01-17 | E-GEOD-12764 | biostudies-arrayexpress
TranscriptomicsGene expression comparison of liver tissue from C57BL/6J and KK/HIJ mice
A QTL intercross was performed bewteen C57BL/6J and KK/HIL for albuminurea, asthma and cardiovascular related phenotypes. Several QTL were identified for most phenotypes. We performed microarray analysis from liver samples to identify genes differentially expressed between the parental strains. The ...
ORGANISM(S): Mus musculus 
2012-10-18 | E-GEOD-37429 | biostudies-arrayexpress
TranscriptomicsTranscription profiling of human (51) breast cancer cell lines
Basal gene expression levels were determined by global gene expression profiling of breast cancer cell lines. Molecular subtype was determined using gene expression and HER2 status assesses by HER2 FISH analysis. Experiment Overall Design: RNA was prepared from cell lines cultured in 10% fetal bovin...
ORGANISM(S): Homo sapiens 
2009-01-17 | E-GEOD-12777 | biostudies-arrayexpress
UnknownNeed for recovery amongst emergency physicians in the UK and Ireland: a cross-sectional survey.
Not available
S-EPMC7607596 | biostudies-literature
UnknownAdd-On Treatment With Zilebesiran for Inadequately Controlled Hypertension: The KARDIA-2 Randomized Clinical Trial.
Not available
S-EPMC12120674 | biostudies-literature
UnknownA second update on mapping the human genetic architecture of COVID-19.
Not available
S-EPMC10482689 | biostudies-literature
UnknownMapping the human genetic architecture of COVID-19.
Not available
S-EPMC8674144 | biostudies-literature
UnknownSARS-CoV-2 vaccination modelling for safe surgery to save lives: data from an international prospective cohort study.
Not available
S-EPMC7995808 | biostudies-literature
UnknownSARS-CoV-2 infection and venous thromboembolism after surgery: an international prospective cohort study.
Not available
S-EPMC8652887 | biostudies-literature
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