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Scaffold or matrix attachment regions (S/MARs) are found in all eukaryotes. The pattern of distribution and genomic context of S/MARs is thought to be important for processes such as chromatin organization and modulation of gene expression. Despite the importance of such processes, much is unknown a...
ORGANISM(S): Arabidopsis thaliana 
The segregation of maternal centromeres away from the paternal ones during the first division of meiosis depends on the attachment of sister kinetochores to microtubules emanating from the same spindle pole. In budding yeast monopolar attachment requires the recruitment to kinetochores of a protein ...
ORGANISM(S): Saccharomyces cerevisiae 
A scaffold attachment factor PHM-2 regulates synaptic transmission through SLO-2 potassium channel in C. elegans
Analysis of gene expression by RNA-seq upon siRNA mediated knockdown of scaffold attachment factor A (SAF-A) versus control siRNA in RPE1 cells at 24 hour and 48 hour time points post transfection reveals SAF-A loss does not impact on gene transcription
ORGANISM(S): Homo sapiens 
2017-06-01 | GSE98541 | GEO
RNA-seq analysis of scaffold attachment factor A (SAF-A) knockdown in RPE1 cells
Scaffold attachment factor B (SAFB) proteins are evolutionarily conserved DNA/RNA binding proteins that are involved in multiple processes of gene expression. These proteins are broadly expressed with particular high expression observed in the nervous system. However, their physiological roles in ne...
ORGANISM(S): Caenorhabditis elegans 
2026-01-15 | GSE315272 | GEO
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