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TranscriptomicsRNA-seq of murine LUAD tumors on control diet or alpha-ketoglutarate diet for 16-weeks compared by sex
12-week old B6 Kras-LUAD mice were maintained on a control diet or alpha-ketoglutarate diet for 16-weeks before LUAD tumors were collected and used for bulk RNA-sequencing.
ORGANISM(S): Mus musculus 
2026-09-01 | E-MTAB-15597 | biostudies-arrayexpress
TranscriptomicsCDDP treatment of U2OS cells with NCOR and SMRT knock-down
We detected an interaction between checkpoint kinase Chk2 and some members of the NCOR/SMRT co-repressor complex. In order to study the role of gene repression in the checkpoint response to DNA damage, we performed RNA profiling in NCOR or SMRT knockdown cells after treztment with cisplatin. U2OS ce...
ORGANISM(S): Homo sapiens 
2012-02-06 | E-GEOD-34226 | biostudies-arrayexpress
TranscriptomicsEstrogen Receptor Beta Impacts Hormone-Induced Alternative mRNA Splicing in Breast Cancer Cells
Estrogens play an important role in breast cancer (BC) development and progression, where the two isoforms of the estrogen receptor (ER? and ER?) are generally co-expressed and mediate the effects of these hormones in cancer cells. ER? has been suggested to exert an antagonist role toward the oncoge...
ORGANISM(S): Homo sapiens 
2015-09-01 | E-GEOD-64590 | biostudies-arrayexpress
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