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UnknownOligomerization of SCFTIR1 Is Essential for Aux/IAA Degradation and Auxin Signaling in Arabidopsis.
Not available
S-EPMC5019376 | biostudies-literature
UnknownAuxin-induced SCFTIR1-Aux/IAA interaction involves stable modification of the SCFTIR1 complex.
Not available
S-EPMC514484 | biostudies-literature
ProteomicsDegron flexibility enforces auxin sensing
Cullin RING-type E3 ubiquitin ligase SCFTIR1/AFB1-5 and their ubiquitylation targets, AUX/IAAs, sense auxin concentrations in the nucleus. TIR1 binds a surface- exposed degron in AUX/IAAs promoting their ubiquitylation and rapid auxin-regulated proteasomal degradation. Here, we resolved TIR1·auxin·I...
ORGANISM(S): Arabidopsis thaliana (Mouse-ear cress) 
2020-05-27 | PXD015392 | Pride
Degron Auxin Phytohormones Aux/iaa Scftir1 Intrinsic disorder Allostery 
ProteomicsVariation in auxin sensing guides AUX/IAA repressor ubiquitylation and destruction
Auxin is a drug-like small molecule and morphogen that triggers the formation of SCFTIR1/AFB-AUX/IAA co-receptor complexes leading to ubiquitylation and proteasome-dependent degradation of AUX/IAA transcriptional repressors in plants. Here, we systematically dissect auxin sensing by SCFTIR1-IAA6 and...
ORGANISM(S): Arabidopsis thaliana (Mouse-ear cress) 
2017-06-14 | PXD004027 | Pride
Phytohormone Ubiquitylation Auxin Scf-type e3 ligase Ubiquitination Tir1/afbs Proteolysis Aux/iaa 
UnknownCOP9 signalosome- and 26S proteasome-dependent regulation of SCFTIR1 accumulation in Arabidopsis.
Not available
S-EPMC2658085 | biostudies-literature
UnknownVariation in auxin sensing guides AUX/IAA transcriptional repressor ubiquitylation and destruction.
Not available
S-EPMC5467235 | biostudies-literature
UnknownRegulation of SCFTIR1/AFBs E3 ligase assembly by S-nitrosylation of Arabidopsis SKP1-like1 impacts on auxin signaling.
Not available
S-EPMC6076216 | biostudies-literature
UnknownIdentification of an SCF ubiquitin-ligase complex required for auxin response in Arabidopsis thaliana.
Not available
S-EPMC316846 | biostudies-literature
UnknownAUX1-mediated root hair auxin influx governs SCFTIR1/AFB-type Ca2+ signaling.
Not available
S-EPMC5862985 | biostudies-literature
UnknownGenetic analysis of CAND1-CUL1 interactions in Arabidopsis supports a role for CAND1-mediated cycling of the SCFTIR1 complex.
Not available
S-EPMC2448860 | biostudies-literature
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