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TranscriptomicsMapping of Three Genetic Determinants of Susceptibility to Estrogen-Induced Mammary Cancer within the Emca8 Locus on Rat Chromosome 5
We are using the ACI rat model of 17beta-estradiol induced mammary cancer to define the mechanisms through which estrogens contribute to breast cancer development; identify and functionally characterize the genetic variants that determine susceptibility; and define the hormone-gene-environment inter...
ORGANISM(S): Rattus norvegicus 
2013-02-08 | E-GEOD-39788 | biostudies-arrayexpress
UnknownPemigatinib in previously treated solid tumors with activating FGFR1-FGFR3 alterations: phase 2 FIGHT-207 basket trial.
Not available
S-EPMC11186762 | biostudies-literature
MetabolomicsMetabolic Phenotyping and Strain Characterisation of Pseudomonas aeruginosa Isolates from Cystic Fibrosis Patients Using Rapid Evaporative Ionisation Mass Spectrometry
Rapid evaporative ionisation mass spectrometry (REIMS) is a novel technique for the real-time analysis of biological material. It works by conducting an electrical current through a sample, causing it to rapidly heat and evaporate, with the analyte containing vapour channelled to a mass spectrometer...
2022-01-26 | MTBLS644 | MetaboLights
TranscriptomicsMouse HCC model
A mouse model of HCC has been developed based on the reported inactivation of the RB pathway in the majority of human HCC. This mouse model harbors floxed alleles of Rb and p130 genes, as well as germline mutation of the p107 gene. Various strategies to activate the activity of a Cre recombinase lea...
ORGANISM(S): Mus musculus 
2010-07-30 | E-GEOD-19004 | biostudies-arrayexpress
TranscriptomicsElucidating the Linezolid response of Staphylococcus aureus USA300 by a holistic study
The translation inhibitor Linezolid is an important antibiotic of last resort against multiresistant gram-positive pathogens including MRSA. Linezolid is reported to specifically inhibit extracellular virulence factors, but the molecular cause is unknown. To elucidate the physiological response of S...
ORGANISM(S): Staphylococcus aureus 
2016-02-22 | E-GEOD-65209 | biostudies-arrayexpress
UnknownLandscape of transcription in human cells.
Not available
S-EPMC3684276 | biostudies-literature
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