Schirmer V V - OmicsDI

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Unknown (107)
Proteomics (17)
Genomics (12)
Metabolomics (3)
Transcriptomics (1)
Genomic (1)

Organisms

Homo sapiens (23)
Mus musculus (2)
Caulobacter vibrioides NA1000 (1)
Danio rerio (1)
Triticum aestivum (1)

Repository

pride (15)
EGA (12)
MetaboLights (3)
MassIVE (2)
biostudies-arrayexpress (1)
dbGaP (1)

Tissue

Tear (6)
Cell culture (2)
Early embryonic cell (1)
Tear secreting cell (1)

Disease

Amyotrophic lateral sclerosis (1)
Aniridia (1)
Diabetes (1)
Neurotrophic keratoconjunctivitis (1)
Retinopathy (1)
Type 1 diabetes mellitus (1)

Technology Type

Mass Spectrometry (15)
Bottom-up proteomics (8)
Data-independent acquisition (5)
Shotgun proteomics (5)
Data-dependent acquisition (3)
Mass spectrometry assay (2)
Unknown (1)
Mass spectrometry (1)

Instrument Platform

LTQ (2)
Liquid Chromatography MS - negative - reverse-phase (2)
Liquid Chromatography MS - positive - reverse-phase (2)
Flow injection analysis MS - (1)

Publication Date

2026 (7)
2025 (4)
2016 (2)
2022 (2)
2011 (1)
2018 (1)
2021 (1)
2024 (1)
2023 (1)
2020 (1)

CHEBI ID

CHEBI:10022 (1)
CHEBI:10075 (1)
CHEBI:10137 (1)
CHEBI:10366 (1)
CHEBI:10368 (1)
CHEBI:10432 (1)
CHEBI:121564 (1)
CHEBI:12427 (1)
CHEBI:125536 (1)
CHEBI:12777 (1)
CHEBI:131691 (1)
CHEBI:131692 (1)
CHEBI:131743 (1)
CHEBI:132966 (1)
CHEBI:132983 (1)
CHEBI:133086 (1)
CHEBI:133094 (1)
CHEBI:133343 (1)
CHEBI:133348 (1)
CHEBI:133478 (1)
CHEBI:133512 (1)
CHEBI:133515 (1)
CHEBI:133617 (1)
CHEBI:133763 (1)
CHEBI:134126 (1)
CHEBI:134254 (1)
CHEBI:134287 (1)
CHEBI:134442 (1)
CHEBI:134515 (1)
CHEBI:134548 (1)

Metabolite Name

(+)-(1R,2R)-1,2-Diphenylethane-1,2-diol (1)
(+)-Isoxanthochymol (1)
(+)-O-Methylarmepavine (1)
(+)-Setoclavine (1)
(+)-Zeylenol (1)
(+-)-(Z)-2-(5-Tetradecenyl)cyclobutanone (1)
(+-)-3-Hydroxynonanoic acid (1)
(+-)-Anisoxide (1)
(+-)-threo-1-(p-Hydroxyphenyl)propylene glycol 4'-glucoside (1)
(+/-)-3-[(2-methyl-3-furyl)thio]-2-butanone (1)
(-)-Epiafzelechin 3-gallate (1)
(-)-Gossypol (1)
(-)-Nopol (1)
(-)-erythro-Anethole glycol 1-glucoside (1)
(-)-trans-Carveol (1)
(-)-trans-Carveol glucoside (1)
(10S,11S)-Pterosin C (1)
(12S,15S)-15-O-Demethyl-10,29-dideoxy-11,12-dihydro-striatin C (1)
(1R,3R,4R,5S,6S,8x)-1-Acetoxy-8-angeloyloxy-3,4-epoxy-5-hydroxy-7(14),10-bi... (1)
(1R,3S,4S,6R)-6,9-Dihydroxyfenchone 6-O-b-D-glucoside (1)
(1Z,4Z)-1,5-bis(4-hydroxyphenyl)-1,4-pentadiene (1)
(1xi,3xi)-1,2,3,4-Tetrahydro-1-methyl-beta-carboline-3-carboxylic acid (1)
(2-Naphthalenyloxy)acetic acid (1)
(20R)-Ginsenoside Rh2 (1)
(2R,2'S)-Isobuteine (1)
(2R,3R,4R)-2-Amino-4-hydroxy-3-methylpentanoic acid (1)
(2R,3S)-Piscidic acid (1)
(2S,4R,6S)-2-[2-(4-Hydroxy-3-methoxyphenyl)ethyl]tetrahydro-6-(4-hydroxy-3,5-dimethoxyphenyl)-2H-pyran-4-ol (1)
(2S,4S,6S)-2-[2-(4-Hydroxy-3-meyhoxyphenyl)ethyl]tetrahydro-6-(4,5-dihydroxy-3-methoxyphenyl)-2H-pyran-4-ol (1)
(2xi,6xi)-7-Methyl-3-methylene-1,2,6,7-octanetetrol (1)

Study type

Transcription profiling by array (1)

Release Date

2020 (15)
2022 (14)
2025 (12)
2024 (12)
2023 (11)
2021 (10)
2015 (6)
2019 (5)
2018 (5)
2017 (5)
2014 (3)
2012 (3)
2016 (2)
2013 (2)
2011 (1)
2010 (1)
2009 (1)

Lab affiliation

Centre for Ocular Regeneration (CORE), Prof. Brien Holden Eye Research Centre (BHERC), L V Prasad Eye Institute, Hyderabad, Telangana, India (2)
LBPC-PPC, Montpellier University, IRMB CHU Montpellier, INM INSERM, Montpellier, Occitanie, France (2)
Allegheny Health Network (1)
Bavarian Center for Biomolecular Mass Spectrometry (BayBioMS) Technical University of Munich (TUM) Gregor-Mendel-Straße 4 85354 Freising GERMANY (1)
Brunel University London (1)
Core Facility Proteomics, Department of Clinical Chemistry, University Medical Center Goettingen, Germany (1)
Department ogf Pharmacy, University "G. d'Annunzio", Chieti, Italy (1)
Diabetes Center, Division of Endocrinology, Diabetes and Metabolism, First Department of Pediatrics, National and Kapodistrian University of Athens Medical School, “Aghia Sophia” Children’s Hospital, Athens, Greece (1)
Head of Bioanalytics Group, Department of Environmental Toxicology (Utox), Eawag – Swiss Federal Institute of Aquatic Science and Technology, 8600 Duebendorf, Switzerland (1)
Proteomics Core Facility Biozentrum, University of Basel Klingelbergstrasse 50/70 CH-4056 Basel / Switzerland (1)
Section Mass Spectrometry and Proteomics, University Medical Center Hamburg-Eppendorf, Hamburg, Germany (1)
Univ Coimbra, Coimbra Institute for Clinical and Biomedical Research (iCBR), Faculty of Medicine, Coimbra, Portugal. (1)
University of Manchester Faculty of Biology, Medicine and Health Division of Cancer Sciences (1)

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Association of IL-8 and IL-18 Expression with Histone-Associated NETosis in Aqueous-Deficient and Evaporative Dry Eye Disease

Purpose: Dry eye disease (DED) is a chronic inflammatory disorder of the ocular surface; however, the upstream immune mechanisms contributing to DED are complex and unclear. This study aimed to identify differentially expressed tear fluid proteins in patients with DED and elucidate the underlying di...

ORGANISM(S): Homo sapiens (Human)

2026-09-07 | PXD075862 | Pride

Association of IL-8 and IL-18 Expression with Histone-Associated NETosis in Aqueous-Deficient and Evaporative Dry Eye Disease

ORGANISM(S): Homo sapiens (Human)

2026-09-07 | PXD075754 | Pride

Tear proteomics Neutrophil degranulation Histones Ocular surface Dry eye And inflammation

Differential expression of tear film cytokines in Stevens-Johnson syndrome patients and comparative review of literature.

Not available

S-EPMC8446064 | biostudies-literature

MudPIT analysis of HSV-1 infected and mock-infected microsomal membranes and nuclear envelopes

Nuclear envelopes (NEs) and microsomal membranes (MMs) were isolated from HeLa cells infected or not with HSV-1 using well-established procedures as described in: Wilkie GS, et al. (2011) Mol Cell Proteomics 10: M110 003129. Korfali N, et al. (2010) Mol Cell Proteomics 9: 2571-2585. Florens L, Korf...

ORGANISM(S): Homo Sapiens (ncbitaxon:9606) Herpes Simplex Virus (type 1 / Strain 17) (ncbitaxon:10299)

2016-07-05 | MSV000079886 | MassIVE

Tear lipidomics profiling reveals inflammatory dry eye disease-associated lipid metabolic remodeling at the ocular surface

This study aimed to investigate whether inflammatory dry eye disease (DED) is accompanied by abnormal lipid metabolic remodeling at the ocular surface. Tear samples were collected from patients with DED and matched healthy controls. Lipidomics profiling was performed using LC–MS/MS with a standardiz...

2026-04-03 | MTBLS14218 | MetaboLights

Tear lipidomics profiling reveals ocular-surface lipid remodeling associated with organelle stress in a mouse model of inflammatory dry eye disease

This study aimed to determine whether dry eye disease (DED) is accompanied by ocular-surface lipid remodeling and whether such changes converge on organelle stress–associated pathways in a mouse model of inflammatory dry eye. Tear samples were collected from mice and analyzed by LC–MS/MS–based non-t...

2026-04-04 | MTBLS14217 | MetaboLights

Lid Margin Microbiome in Stevens-Johnson Syndrome Patients With Lid Margin Keratinization and Severe Dry Eye Disease.

Not available

S-EPMC11193065 | biostudies-literature

Crystal structure of diethyl (E)-2-[(benzo-furan-2-yl)methyl-idene]succinate.

Not available

S-EPMC4645082 | biostudies-literature

Report of the 23rd Meeting on Signal Transduction 2019-Trends in Cancer and Infection.

Not available

S-EPMC7215334 | biostudies-literature

Tear Proteomics Analysis in Children and Adolescents with Type 1 Diabetes

Fifty-six children and adolescents with type 1 diabetes at least one year after diagnosis, aged 6-17 years old and fifty-six healthy age- and sex-matched subjects were enrolled in this cross-sectional study. Tear samples were collected using Schirmer strips placed on the lower eyelid. The proteomic ...

ORGANISM(S): Homo sapiens (Human)

2024-10-17 | PXD052994 | Pride

Diabetic complications Mass spectrometry Biomarkers Children Glycemic control Tear proteome Diabetic ketoacidosis Type 1 diabetes

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