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TranscriptomicsHuman skeletal muscle fibroblasts and stem cells cultured with rat motor neuron cells
The study was designed to compare whether and how muscle fibroblasts (FIB) and muscle stem cells (MYO) interact with motor neurons. Moreover, we aimed to investigate whether muscle cells, isolated from lifelong exercisers, exerted a protective and supportive effect on motor neurons. These object...
ORGANISM(S): Homo sapiens 
2026-02-21 | E-MTAB-14395 | biostudies-arrayexpress
TranscriptomicsHuman skeletal muscle fibroblasts and stem cells cultured with rat motor neuron cells
The study was designed to compare whether and how muscle fibroblasts (FIB) and muscle stem cells (MYO) interact with motor neurons. Moreover, we aimed to investigate whether muscle cells, isolated from lifelong exercisers, exerted a protective and supportive effect on motor neurons. These object...
ORGANISM(S): Rattus norvegicus 
2026-02-21 | E-MTAB-14397 | biostudies-arrayexpress
TranscriptomicsEffects of human skeletal muscle fibroblast and stem cell media on cultured rat motor neuron cells
The study was designed to compare whether and how muscle fibroblasts (FIB) and muscle stem cells (MYO) interact with motor neurons. Moreover, we aimed to investigate whether muscle cells, isolated from lifelong exercisers, exerted a protective and supportive effect on motor neurons. These object...
ORGANISM(S): Rattus norvegicus 
2026-02-21 | E-MTAB-14399 | biostudies-arrayexpress
TranscriptomicsCircadian analysis of human tendinopathic patella tendon
To identify if genes is regulated by time of day in human tendinopathic tendon, RNAseq analysis was performed on biopsies taken from tendinopathic and contralateral patella tendon 12 hours apart in young tendinopathic subjects (9 AM and 9 PM).
ORGANISM(S): Homo sapiens 
2023-02-09 | E-MTAB-11938 | biostudies-arrayexpress
TranscriptomicsCircadian analysis of human healthy patella tendon
To identify if genes is regulated by time of day in human tendon, RNAseq analysis was performed on biopsies taken from patella tendon 12 hours apart in young healthy subjects (9 AM and 9 PM).
ORGANISM(S): Homo sapiens 
2023-02-09 | E-MTAB-11937 | biostudies-arrayexpress
TranscriptomicsSpatial Transcriptomics of the human musculotendinous unit, the myotendinous junction
Identification of cell types in the interphase between muscle and tendon by Visium Spatial Transcriptomics of four human semitendinous muscle-tendon biopsies. Cell types identified by single nuclei RNA seq on similar tissue were localized in situ with the use of Spatial Transcriptomics.
ORGANISM(S): Homo sapiens 
2023-03-02 | E-MTAB-12530 | biostudies-arrayexpress
TranscriptomicsSingle-nucleus RNA-seq of human tendon and myotendinous junction after acute exercise
Mechanical loading promotes structural and functional improvements in muscle and tendon, protecting against injury at their interface – the myotendinous junction (MTJ) and within the tendon matrix. However, the early cellular and molecular mechanisms underlying these adaptations in humans remain poo...
ORGANISM(S): Homo sapiens 
2025-10-10 | E-MTAB-15400 | biostudies-arrayexpress
TranscriptomicsSingle-nucleus RNA-seq of the human musculotendinous unit, the myotendinous junction
Identification of cell types in the interphase between muscle and tendon by single-nuclei RNA-seq of three human semitendinous muscle-tendon biopsies. With special focus on the myotendinous junction specific myonuclei, transcripts were identified and confirmed to myotendinous junction with immunoflu...
ORGANISM(S): Homo sapiens 
2023-03-02 | E-MTAB-12529 | biostudies-arrayexpress
TranscriptomicsHuman skeletal muscle transcriptome responses to differentiated exercise
The few investigations on exercise-induced global gene expression responses in human skeletal muscle haves typically focused at one specific mode of exercise and few such studies have implemented control measures. However, interpretation on distinct phenotype regulation necessitate comparison betwee...
ORGANISM(S): Homo sapiens 
2014-11-19 | E-GEOD-59088 | biostudies-arrayexpress
TranscriptomicsStrength training with suppressed testosterone level
Human subjects were randomized for treatment with a GnRH-analogue, Goserelin, which suppresses endogenous testosterone or placebo for 12 weeks. Strength training was performed during the last 8 weeks. The suppression of testosterone resulted in an attenuation of the normal muscle adaptation to stren...
ORGANISM(S): Homo sapiens 
2014-09-30 | E-GEOD-43437 | biostudies-arrayexpress
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