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MetabolomicsMulti-omics analysis reveals microbiota-metabolite crosstalk in MASLD pathogenesis in a non-obese murine model

The rising global prevalence of metabolic dysfunction-associated steatotic liver disease (MASLD), including its severe form metabolic dysfunction-associated steatohepatitis (MASH), underscores the urgency to elucidate its pathophysiology. To investigate key metabolic interactions central to MASLD...

2026-03-13 | MTBLS14048 | MetaboLights
UnknownEffect of ischemic preconditioning in skeletal muscle measured by functional magnetic resonance imaging and spectroscopy: a randomized crossover trial.
Not available
S-EPMC3143996 | biostudies-literature
ModelsBegitt2014 - STAT1 cooperative DNA binding - double GAS polymer model
Begitt2014 - STAT1 cooperative DNA binding - double GAS polymer model The importance of STAT1-cooperative DNA binding in type 1 and type 2 interferon signalling has been studies using experimental and modelling approaches. The authors have developed two ODE models to describe STAT1...
2024-09-02 | BIOMD0000000501 | BioModels
ModelsBegitt2014 - STAT1 cooperative DNA binding - single GAS polymer model
Begitt2014 - STAT1 cooperative DNA binding - single GAS polymer model The importance of STAT1-cooperative DNA binding in type 1 and type 2 interferon signalling has been studies using experimental and modelling approaches. The authors have developed two ODE models to describe STAT1...
2024-09-02 | BIOMD0000000500 | BioModels
Manuscript Accepted 
ProteomicsProtein aggregation is a consequence of the dormancy-inducing membrane toxin TisB in Escherichia coli
Protein aggregates occur in all living cells due to misfolding of proteins. In bacteria, protein aggregation is associated with cellular inactivity, which is related to dormancy and tolerance to stressful conditions, including the exposure to antibiotics. In Escherichia coli, the membrane toxin TisB...
ORGANISM(S): Escherichia coli 
2024-10-04 | PXD049478 | Pride
Toxin-antitoxin system Antibiotics Dormancy Protein aggregation Type i toxin 
UnknownCryo-EM reconstruction of a modified human Adenovirus C5
Not available
EMPIAR-10117 | biostudies-other
TranscriptomicsmiRseq Analysis of Human Macrophages Co-cultured with MCF-7 Breast Cancer Cells
Tumor-immune cell interactions shape the immune cell phenotype, with microRNAs (miRs) being crucial components of this crosstalk. How they are transferred, and how they affect their target landscape, especially in tumor-associated macrophages (TAMs), is largely unknown. Here we aimed to define miRo...
ORGANISM(S): Homo sapiens 
2019-02-08 | E-MTAB-6885 | biostudies-arrayexpress
GenomicsGermline variants in the SEMA4A gene predispose to familial colorectal cancer type X
Familial colorectal cancer type X (FCCTX) is characterized by clinical features of hereditary non-polyposis colorectal cancer with a yet undefined genetic background. Here, using an integrative genomics strategy, we identify the SEMA4A p.Val78Met germline mutation in an Austrian kindred with FCCTX. ...
EGAS00001000957 | EGA
TranscriptomicsPhenocopy
Comprehensive in vitro expression profiling of small chemical compound inhibitors of TGFbR1 kinase activity. Additional file E-MTAB-265.additonal.1.zip contains excel file with Taqman data validating the array normalization method
ORGANISM(S): Homo sapiens 
2010-09-14 | E-MTAB-265 | biostudies-arrayexpress
Genomicsena-DATASET-MUG-11-09-2014-07:42:30:338-15 - samples
Exome sequencing of peripheral blood from 4 individuals of a family with familial colorectal cancer type X
EGAD00001001009 | EGA
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