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GenomicsGenome-wide mapping of Nuclear Factor I binding sites using ChIP-Seq in WT and NFI-C knock-out MEFs
The Nuclear Factor I (NFI) family of DNA binding proteins (also called CAAT box transcription factors or CTF) is involved both in replication of adenoviral DNA and in regulation of gene expression. Using chromatin immuno-precipitation and high throughput sequencing (method termed ChIP-Seq) we perfor...
ORGANISM(S): Mus musculus 
2010-04-24 | E-GEOD-15844 | biostudies-arrayexpress
UnknownmicroRNAs are differentially regulated between MDM2-positive and negative malignant pleural mesothelioma.
Not available
S-EPMC4951323 | biostudies-literature
GenomicsStudy of RFX1 and RFX3 binding sites in the mouse genome
The aim of the study was to identify RFX1 and RFX2 binding sites in mouse pancreatic beta cells. Chromatin immunoprecipitation experiments were performed with the mouse MIN6 beta cell line and antibodies raised against RFX1 and RFX3. Immunoprecipitated DNA was sequenced using the Genome Analyzer II ...
ORGANISM(S): Mus musculus 
2015-08-22 | E-GEOD-72272 | biostudies-arrayexpress
UnknownMDM2 is an important prognostic and predictive factor for platin-pemetrexed therapy in malignant pleural mesotheliomas and deregulation of P14/ARF (encoded by CDKN2A) seems to contribute to an MDM2-driven inactivation of P53.
Not available
S-EPMC4453955 | biostudies-literature
UnknownACTB, CDKN1B, GAPDH, GRB2, RHOA and SDCBP Were Identified as Reference Genes in Neuroendocrine Lung Cancer via the nCounter Technology.
Not available
S-EPMC5089548 | biostudies-literature
UnknownMutational analysis of pulmonary tumours with neuroendocrine features using targeted massive parallel sequencing: a comparison of a neglected tumour group.
Not available
S-EPMC4701994 | biostudies-literature
UnknownGene expression profiling of homologous recombination repair pathway indicates susceptibility for olaparib treatment in malignant pleural mesothelioma in vitro.
Not available
S-EPMC6354412 | biostudies-literature
UnknownProcessing Escape Mechanisms Through Altered Proteasomal Cleavage of Epitopes Affect Immune Response in Pulmonary Neuroendocrine Tumors
Not available
S-EPMC6295696 | biostudies-literature
TranscriptomicsTGFβ contributes to impaired exercise response by suppression of mitochondrial key regulators in skeletal muscle
substantial number of people at risk to develop type 2 diabetes could not improve insulin sensitivity by physical training intervention. We studied the mechanisms of this impaired exercise response in 20 middle-aged individuals who performed a controlled eight weeks cycling and walking training at 8...
ORGANISM(S): Homo sapiens 
2016-06-29 | E-GEOD-72462 | biostudies-arrayexpress
TranscriptomicsEvaluation of methods for modeling transcription factor sequence specificity
Genomic analyses often involve scanning for potential transcription-factor (TF) binding sites using models of the sequence specificity of DNA binding proteins. Many approaches have been developed to model and learn a protein’s binding specificity by representing sequence motifs, including the gaps a...
ORGANISM(S): synthetic construct 
2012-12-13 | E-GEOD-42864 | biostudies-arrayexpress
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