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TranscriptomicsA regulatory hierarchy controls the dynamic transcriptional response to extreme oxidative stress in archaea.
Previous work identified the winged helix-turn-helix DNA binding transcription factor (TF) RosR (encoded by VNG0258H gene), which dynamically regulates expression of more than 300 genes in response to oxidative stress in Halobacterium salinarum (Sharma 2012). RosR is required for survival of oxidant...
ORGANISM(S): Halobacterium sp. NRC-1 
2015-02-18 | E-GEOD-58696 | biostudies-arrayexpress
UnknownPhase 1 Dose-Escalation Study of Pegylated Arginine Deiminase, Cisplatin, and Pemetrexed in Patients With Argininosuccinate Synthetase 1-Deficient Thoracic Cancers.
Not available
S-EPMC6141244 | biostudies-literature
TranscriptomicsTopoisomerase function in E. coli replication fork movement
Analysis of topoisomerase function in bacterial replication fork movement: use of DNA microarrays. We used DNA microarrays of the Escherichia coli genome to trace the progression of chromosomal replication forks in synchronized cells. We found that both DNA gyrase and topoisomerase IV (topo IV) prom...
ORGANISM(S): Escherichia coli 
2001-07-30 | E-GEOD-8 | biostudies-arrayexpress
UnknownRaman focal point on Roman Egyptian blue elucidates disordered cuprorivaite, green glass phase and trace compounds.
Not available
S-EPMC9481618 | biostudies-literature
UnknownMulticenter, Phase III, Randomized, Double-Blind, Placebo-Controlled Trial of Pravastatin Added to First-Line Standard Chemotherapy in Small-Cell Lung Cancer (LUNGSTAR).
Not available
S-EPMC5455702 | biostudies-literature
UnknownComparison of a Behavioral Versus an Educational Weight Management Intervention After Renal Transplantation: A Randomized Controlled Trial.
Not available
S-EPMC7004588 | biostudies-literature
MetabolomicsAccumulation of the coumarin scopolin under abiotic stress conditions is mediated by the Arabidopsis thaliana THO/TREX complex
Secondary metabolites are involved in the plant stress response. Among these are scopolin and its active form scopoletin, which are coumarin derivatives associated with reactive oxygen species scavenging and pathogen defence. Here we show that in Arabidopsis thaliana, scopolin accumulation can be in...
2018-02-05 | MTBLS389 | MetaboLights
UnknownA Ligand Selection Strategy Identifies Chemical Probes Targeting the Proteases of SARS-CoV-2.
Not available
S-EPMC7986205 | biostudies-literature
UnknownLinear distributed source modeling of local field potentials recorded with intra-cortical electrode arrays.
Not available
S-EPMC5734682 | biostudies-literature
UnknownA mutation in the human MPDU1 gene causes congenital disorder of glycosylation type If (CDG-If).
Not available
S-EPMC200991 | biostudies-literature
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