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ProteomicsMachine Learning Based Classification of Diffuse Large B-cell Lymphoma Patients by their Protein Expression Profiles
Characterization of tumors at the molecular level has improved our knowledge of cancer causation and progression. Proteomic analysis of their signaling pathways promises to enhance our understanding of cancer aberrations at the functional level, but this requires accurate and robust tools. Here, we ...
ORGANISM(S): Homo Sapiens (ncbitaxon:9606) 
2017-03-30 | MSV000080813 | MassIVE
OtherMachine Learning Based Classification of Diffuse Large B-cell Lymphoma Patients by their Protein Expression Profiles.
Data from ProteomeXchange, PXD ID: PXD002052. Experiment: TRR37, file: folder summary. Published as part of Mol Cell Proteomics. 2015 Aug 26 . From the Abstract: {{i}} ... Here, we develop a state of the art quantitative mass spectrometric pipeline to characterize formalin-fixed paraffin-embedded (...
ORGANISM(S): Homo_sapiens_viruses, Human 
GPM32320017943 | GPMDB
Resource Reanalysis 
TranscriptomicsContinuous T cell receptor signals maintain a functional regulatory T cell pool
During development, thymocytes bearing a moderately self-reactive T cell receptor (TCR) can be selected to become regulatory T (Treg) cells. Several observations suggest that also in the periphery mature Treg cells continuously receive self-reactive TCR signals. However, the importance of this inhe...
ORGANISM(S): Mus musculus 
2014-10-21 | E-GEOD-62532 | biostudies-arrayexpress
ProteomicsSuper-SILAC Allows Classification of Diffuse Large B-cell Lymphoma Subtypes by Their Protein Expression Profiles
Correct classification of cancer patients into subtypes is a prerequisite for acute diagnosis and effective treatment. Currently this classification relies mainly on histological assessment, but gene expression analysis bymicroarrays has shown great promise. Here we show that high accuracy, quantita...
ORGANISM(S): Homo Sapiens (ncbitaxon:9606) 
2016-03-10 | MSV000079572 | MassIVE
OtherSuper-SILAC allows classification of diffuse large B-cell lymphoma subtypes by their protein expression profiles.
Data from ProteomeXhchange, PXD ID: PXD002098. Experiment: TMD8(2), file: folder summary. Published as part of Mol Cell Proteomics. 2012 May;11(5):77-89 . From the Abstract: {{i}} ... Here we show that high accuracy, quantitative proteomics can robustly segregate cancer subtypes directly at the lev...
ORGANISM(S): Homo_sapiens_viruses, Human 
GPM32310019515 | GPMDB
Resource Reanalysis 
TranscriptomicsEbf2-GFP in IEO cells
Comparison of Ebf2-expressing bone marrow mesenchymal cells from Ebf2-GFP heterozgous and Ebf2-GFP homozygous (=knock-out) mice
ORGANISM(S): Mus musculus 
2017-12-17 | E-MTAB-2254 | biostudies-arrayexpress
ProteomicsARID1A mutations protect follicular lymphoma from FAS-dependent immune surveillance by reducing RUNX3/ETS1-driven FAS-expression
The cell death receptor FAS and its ligand (FASLG) play crucial roles in the selection of B cells during the germinal center (GC) reaction. Failure to eliminate potentially harmful B cells via FAS can lead to lymphoproliferation and the development of B cell malignancies. The classic form of follicu...
ORGANISM(S): Homo Sapiens 
PXD041408 | panorama
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