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ProteomicsBlinded rerun of infected and uninfected pig wound fluids
This is a blinded rerun of 12 pig wound fluid samples from the study at PXD048892, looking at differences in wound fluid peptidomes based on infecting pathogen.The raw data alongside code for easily loading and processing the data and creating relevant figures is available at https://github.com/Fred...
ORGANISM(S): Sus scrofa domesticus (domestic pig) 
2025-05-13 | PXD055074 | Pride
Wound fluid Proteomics Infection Porcine Pig 
ProteomicsPeptide clustering enhances large-scale analyses and reveals proteolytic signatures in mass spectrometry data
Recent advances in mass spectrometry-based peptidomics have catalyzed the identification and quantification of thousands of endogenous peptides across diverse biological systems. However, the vast peptidomic landscape generated by proteolytic processing poses several challenges for downstream analys...
ORGANISM(S): Homo sapiens (Human) Sus scrofa domesticus (domestic pig) 
2024-07-13 | PXD048892 | Pride
Peptidomics Wound fluid Peptides Human Infection Porcine 
ProteomicsStapling a host defense peptide for boosted dual targeting of CD14 and bacterial LPS
Excessive Toll like receptor (TLR) and NF-kB activation during infection causes the overactivation of inflammatory pathways seen in sepsis. Thrombin-derived C-terminal peptides (TCP) target both bacteria and the resulting TLR-mediated inflammatory response during infection. The present study describ...
ORGANISM(S): Homo Sapiens (ncbitaxon:9606) 
2022-11-30 | MSV000090815 | MassIVE
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