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Treatment induced senescence (TIS) is a terminal cell cycle arrest program, increasingly recognized as a tumor suppressor mechanism complementing apoptosis in response to standard chemotherapy regimens. In particular cells with blocked apoptotic pathways rely on senescence as the only remaining fail...
ORGANISM(S): Mus musculus 
Oncogene-induced senescence (OIS), a terminal cell cycle block countering (pre)neoplastic lesions, is characterised on the molecular level by trimethylated histone H3 lysine 9 (h3K9me3), a transcriptionally repressive chromatin mark linked to silencing of S-phase-promoting genes. Whether H3K9-govern...
ORGANISM(S): Mus musculus 
Expression data from Adriamycin-treated Emu-myc Suv39h1-/- B-cell lymphoma
Global expression profiling of treatment-induced senescence in mouse Emu-myc B-cell lymphomas
Expression data from treatment-induced senescence in mouse Emu-myc B-cell lymphoma model.
Expression data from treatment-induced senescence in mouse Emu-myc B-cell lymphoma model
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